Digital Health Assistant & Symptom Checker | Symptoma
0%
Restart

Are you sure you want to clear all symptoms and restart the conversation?

About COVID-19 Jobs Press Scholarship Terms Privacy Imprint Medical Device Language
Languages
Suggested Languages
English en
Other languages 0
2.1
Vinblastine Poisoning
Poisoning by Vinblastine

Presentation

This work presents an unusual fatal case of overdose subsequent to an accidental massive administration of Vinblastine (90 mg instead of 9 mg), slow bolus (five minutes), to a 33-year-old woman who suffered from Hodgkin’s Lymphoma. [semanticscholar.org]

Case report A 2-year-old girl with body weight of 8 kg, who presented with prolonged fever and generalized body pain was brought to our outpatient oncology clinic for further workup. [ncbi.nlm.nih.gov]

Skin

  • Dermatitis

    Other reported adverse effects in cases of VBL overdose are inappropriate ADH secretion (SIADH), cardiac toxicity, dermatitis, fever, hair loss, central and peripheral neuropathy, myalgia, seizure, coma, and paralytic ileus (2-5). [ncbi.nlm.nih.gov]

Workup

Case report A 2-year-old girl with body weight of 8 kg, who presented with prolonged fever and generalized body pain was brought to our outpatient oncology clinic for further workup. [ncbi.nlm.nih.gov]

Treatment

The treatments are mainly supportive to alleviate the predominant drugs’ adverse effects such as neurotoxicity, ileus and myelosuppression. [ncbi.nlm.nih.gov]

Broad spectrum antibiotic treatment and intravenous imminoglobulin was given for severe febrile notropenia. On day 4th, the girl also suffered a peripheral neuropatic pain which was controlled by gabapentine. [journals.lww.com]

Spagnolo and Cristina Mondello and Francesca Indorato and Luigi Cardia and Cataldo Raffino and Giulio Cardia and Giovanni Bartoloni}, journal={Australian Journal of Forensic Sciences}, year={2017}, volume={49}, pages={704 - 710} } The pharmacological treatment [semanticscholar.org]

Languages
Suggested Languages
English en
Other languages 0
2.1
About Symptoma.com COVID-19 Jobs Press Scholarship
Contact Terms Privacy Imprint Medical Device