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Viral Lower Respiratory Infection
Viral LRI

Presentation

The most prevalent virus was respiratory syncytial virus (RSV) present in 49 (32%) of the total viral isolates. This was followed by parainfluenza virus present in 43(28%) of the isolates. [bps.uonbi.ac.ke]

However, we believe that this result matches what we would expect on the basis of the clinical presentation of influenza virus infection. [ajronline.org]

At presentation, the mean (SD) duration of the illness in patients was 8.7 (5.5) days. [thorax.bmj.com]

The present study will help to highlight the disease burden of LRTI due to viruses and identify the type of virus causing it. [scitechnol.com]

A unique presentation of ANE has not previously been reported in association with an RSV infection. All patients had a positive outcome and recovered fully with supportive management. Issues [platform.almanhal.com]

Respiratoric

  • Cough

    The following symptoms may occur Abnormal fatigue A sore, painful throat A blocked and/ or runny nose A Headache A slight temperature Cough Especially coughing is a very unpleasant symptom. [montavit.com]

    You can usually treat your symptoms at home. get plenty of rest drink lots of water to loosen any mucus and make it easier to cough up drink a hot lemon and honey drink to help soothe a cough (not suitable for babies) gargle with warm salty water if you [nhs.uk]

    If you have any of the following symptoms then you should see a doctor within 48 hours: coughing up blood or bloody mucus fever, cough and feeling generally unwell chest pain cough lasting more than three weeks unexplained weight loss lumps in your neck [your.md]

  • Dry Cough

    These include: Congestion or runny nose Dry cough Sore throat Low-grade fever Mild headache Mild LRTIs can sometimes become more severe, leading to pneumonia, bronchitis, or other more serious infections. [templehealth.org]

    Less severe infections can have symptoms similar to the common cold, including: a stuffed up or a runny nose a dry cough a low fever a mild sore throat a dull headache In more severe infections, symptoms can include: a severe cough that may produce phlegm [medicalnewstoday.com]

  • Hoarseness

    […] obstructive pulmonary disease (COPD), bronchitis, asthma, influenza, viral syndrome, respiratory failure and congestive heart failure with infection, pneumonia or symptoms of wheezing, dyspnea, cough, sputum production, nasal congestion, sore throat, and/or hoarseness [contagionlive.com]

    If laryngitis develops (larynx=voice box + itis=inflammation), the patient may lose their voice or become hoarse. It is often difficult to know the difference between an acute upper respiratory infection and influenza (seasonal flu ). [emedicinehealth.com]

    Often preceded by coryzal symptoms, followed by fever, hoarseness, cough and signs of upper airway obstruction, namely stridor. This condition may be life threatening in young children. [virology.uct.ac.za]

    Tonsillitis usually presents with a sore throat that can feel worse when swallowing, high temperature (>38°C), coughing, hoarseness of voice, and headache. 33 Symptoms usually last for 3–4 days before the child recovers. [dovepress.com]

    Clinical Manifestations The syndrome of epiglottitis begins with the acute onset of fever, sore throat, hoarseness, drooling, dysphagia and progresses within a few hours to severe respiratory distress and prostration. [ncbi.nlm.nih.gov]

  • Acute Cough

    […] with acute cough and respiratory tract infection in primary care[6]. [patient.info]

    Cough is the most common symptom bringing patients to the primary care physician's office, and acute bronchitis is usually the diagnosis in these patients. [aafp.org]

    "Beta2-agonists for acute cough or a clinical diagnosis of acute bronchitis". The Cochrane Database of Systematic Reviews (9): CD001726. doi:10.1002/14651858.CD001726.pub5. PMID 26333656. ^ a b c Antibiotic Expert Group. [en.wikipedia.org]

Workup

Investigations included an extensive etiological workup on nasopharyngeal aspirates. Immunofluorescence technique was used to detect the viral pathogens. [academicjournals.org]

Treatment

Currently treatment of VRTI is essentially supportive and no specific and efficient treatments are known. [clinicaltrials.gov]

Acute exacerbations of chronic bronchitis Acute exacerbations of chronic bronchitis are often due to viral infection and do not require treatment with antimicrobials. [apps.who.int]

Surfactant and small interfering RNAs may be promising treatment options in the future. Prospective studies however are needed to demonstrate their effect. [nvic.nl]

Treatments Treatments Treatment for lung infections depends on how severe the illness is and whether the infection is bacterial, viral or fungal. Most bacterial infections are treated with a full course of prescribed antibiotics. [rileychildrens.org]

Most RTIs get better without treatment, but sometimes you may need to see your GP. [nhs.uk]

Prognosis

Rhinosinusitis The prognosis is generally favorable for acute rhinosinusitis, and many cases appear to resolve even without antibiotic therapy. [emedicine.medscape.com]

Complications and prognosis Complete resolution after treatment should be expected in the vast majority of cases. [patient.info]

Upper Respiratory Infection Prognosis (Outlook) Upper respiratory infections are a common occurrence and most people will get two to four colds per year. [emedicinehealth.com]

Etiology

10,387 (36.6%) were positive for at least one etiology. [journals.plos.org]

Lung puncture in the etiological diagnosis of pneumonia. Am J Dis Child. 1971;122:278-282. Google Scholar | Crossref | Medline 33. Escobar JA, Dover AS, Duenas A, et al. Etiology of respiratory tract infections in children in Cali, Columbia. [journals.sagepub.com]

Paediatric patients with known etiology of LRTI were not included in the study. [scitechnol.com]

There is little information on the viral and bacterial etiology of severe pneumonia in Sudan where the disease burden is particularly high. [academicjournals.org]

Epidemiology

Epidemiology of respiratory syncytial virus, influenza A, adenovirus, and parainfluenza virus in the Netherlands, 1997-2003 Respiratory syncytial virus and influenza viruses Worldwide, respiratory syncytial virus is … View Full Text [bmj.com]

Harris JA, Huskins WC, Langley JM, Siegel JD Pediatric Special Interest Group of the Society for Healthcare Epidemiology of A. [ncbi.nlm.nih.gov]

Pathophysiology

Developmental aspects of respiratory anatomy and mechanics are of great importance in the pathophysiology of LRTI and explain why children with the condition are more susceptible to respiratory insufficiency compared to adults. [nvic.nl]

The student will be able to differentiate among the epidemiologies of infections caused by these organisms, and the underlying pathophysiology of disease. [accessmedicine.mhmedical.com]

Epidemiology Has incidence of 1-3/1000 and, of those admitted to hospital the mortality is 10% Pathophysiology Basically, viruses or bacteria gets into your lower respiratory tract and you get an infection. Go figure. [medrevise.co.uk]

Pathophysiology There is no hard and fast definition of LRTI that is universally agreed upon. Essentially, it is inflammation of the airways/pulmonary tissue, due to viral or bacterial infection, below the level of the larynx. [patient.info]

Respiratory syncytial virus puzzle: clinical features, pathophysiology, treatment and prevention. J Pediatr, 121 (1992), pp. 503-510 [29.] A. Sahib El-Radhi, W. Barry, S. Patel. Association of fever and severe clinical course in bronchiolitis. [analesdepediatria.org]

Prevention

(November 6, 2017) Centers for Disease Control and Prevention. CDC Features: Pneumonia can be prevented—vaccines can help. Available online at https://www.cdc.gov/Features/Pneumonia/. Accessed on September 8, 2018. [labtestsonline.it]

More research is needed to see if taking a vitamin D supplement can help to prevent respiratory infections. [vitamindcouncil.org]

Centers for Disease Control and Prevention (CDC). [mlo-online.com]

Although this may not ease your own symptoms, it will prevent you from spreading infectious diseases. Avoid touching your face, especially your eyes and mouth, to prevent introducing germs into your system. [healthline.com]

Share on Pinterest Washing the hands frequently can help prevent lower respiratory tract infections. [medicalnewstoday.com]

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