Upper respiratory tract infections are frequent illnesses in the general population. They are caused by either viruses or bacteria. A viral infection may become complicated subsequently by bacteria. The location of the disease dictates its gravity, as viral upper respiratory tract infections range from simple ones, like viral nasopharyngitis to more severe ones, like rhinosinusitis, epiglottitis, laryngotracheitis and otitis media.
In viral nasopharyngitis patients have profuse nasal discharge , fever, halitosis, mouth breathing leading to dry mouth, hyposmia, sneezing and odynophagia, symptoms that occur 2-3 days after inoculation and last for 7-14 days, depending on the age of the patient . Nasal secretions are initially clear and after 2-3 days turn green or yellow, which may signify a superimposed bacterial infection . Examination of the uvula and posterior pharynx reveals inflammation. Cough may result from postnasal drip. Conjunctivitis and photophobia may accompany ocular pain.
Viral rhinosinusitis  is also characterized by nasal discharge with mucopurulent secretion that does not improve with decongestants or antihistamines administration. Facial or dental pain related to the affected sinus raise rhinosinusitis suspicion. Other symptoms include sore throat, dry mouth, cough, posttussive emesis, hyposmia, and fatigability.
Epiglottitis may represent a potential lethal emergency . It is characterized by an acute onset of symptoms like fever, dyspnea, fatigability, odynophagia- as severe as to prevent saliva swallowing, leading to drooling, dysphonia or total voice loss . Severe episodes are accompanied by respiratory distress, manifested as tachypnea, tachycardia, perioral cyanosis and use of accessory respiratory muscles.
Acute viral otitis media also has a rapid onset , consisting of fever, otalgia, difficulty sleeping, irritability, headache, loss of appetite, fluid drainage from the ear and diminished hearing .
All viral upper respiratory tract infections can cause cervical lymphadenopathy. Specific etiologies lead to specific signs: mononucleosis is accompanied by splenomegaly and hepatomegaly, herpes virus infection causes palatal vesicles, vesicles located on the uvula, palate and anterior tonsillar pillars suggest herpangina. Tonsil hypertrophy is a common finding. Cough may be severe enough to produce conjunctival hemorrhages.
Entire Body System
It is characterized by an acute onset of symptoms like fever, dyspnea, fatigability, odynophagia- as severe as to prevent saliva swallowing, leading to drooling, dysphonia or total voice loss. [symptoma.com]
We report the cases of eight military patients with fever ( 38 C) induced by viral upper respiratory tract infection (URTI) who requested treatment with acupuncture in the military medical service room. [ncbi.nlm.nih.gov]
These were ‘fever’ ( P 0.01) and ‘low energy, tired’ ( P 0.04). [academic.oup.com]
Sudden Infant Death Syndrome
These results are relevant to sudden infant death syndrome (SIDS). The combination of prone sleeping and URTI reproduces the nasopharyngeal flora seen in SIDS. [ncbi.nlm.nih.gov]
Carriage of Haemophilus influenzae and Streptococcus pneumoniae in healthy Chinese and Vietnamese children in Hong Kong. Acta paediatr (Oslo, Norway: 1992). 1995;84(11):1262–7. 19. Dhakal R, Sujatha S, Parija SC, Bhat BV. [bmcinfectdis.biomedcentral.com]
Two previous studies incorporating capsaicin cough challenge methodology have demonstrated that cough reflex sensitivity is transiently enhanced during URI. These studies used single measurements of cough reflex sensitivity during the URI period. [ncbi.nlm.nih.gov]
Cough may result from postnasal drip. Conjunctivitis and photophobia may accompany ocular pain. [symptoma.com]
European Respiratory Journal 2011 38: p3510; DOI: Abstract One previous study has demonstrated that cough reflex sensitivity to inhaled capsaicin is transiently enhanced during acute viral respiratory tract infection (URI) by comparing single cough reflex [erj.ersjournals.com]
Measurement of cough reflex sensitivity Measurement of cough reflex sensitivity has allowed insight into the effects of viral URI on human cough reflex sensitivity. [jtd.amegroups.com]
Other symptoms include sore throat, dry mouth, cough, posttussive emesis, hyposmia, and fatigability. Laryngeal involvement is recognized by hoarseness or voice loss and dry cough. Epiglottitis may represent a potential lethal emergency. [symptoma.com]
Clinical and psychosocial predictors of illness duration from randomised controlled trial of prescribing strategies for sore throat. Br Med J 1999 ; 319 (7212): 736 –737. 6 Hay AD, Wilson A, Fahey T, Peters TJ. [academic.oup.com]
Pharyngitis Pharyngitis is more commonly known as a sore throat. Sometimes a sore throat is a symptom of a wider respiratory illness such as the common cold, but it can also be due to an infection only in your pharynx (throat). [gleneagles.com.sg]
throat, conjunctivitis–with adenovirus infections; sore throat with pain on swallowing, fever, absence of cough, and exposure to a person with streptococcal pharyngitis in the prior 2 wks support Dx of GABHS-related pharyngitis; Pts with acute sinusitis [medical-dictionary.thefreedictionary.com]
[…] angiotensin I og angiotensin en Adverse Drug Reaction acarodermatitis, bronchitis, bronchopneumonia, cellulitis, cystitis, ear infection, eye infection, influenza, localised infection, nasopharyngitis, onychomycosis, otitis media, otitis media chronic, pharyngitis [da.glosbe.com]
[…] lesions,” tender anterior cervical lymphadenopathy, and occasionally a scarlatiniform rash; pharyngeal or palatal vesicles and ulcers (herpangina) suggest enteroviral or herpetic pharyngitis; pharyngeal exudates are most common in GABHS-related pharyngitis [medical-dictionary.thefreedictionary.com]
Acute Pharyngitis MicrobiologyAcute Pharyngitis Microbiology Commonest bacterial etiology: GAS: 5 – 15 % of sore throat visits in adults (20 – 30 % in children). 27. [slideshare.net]
Acute pharyngitis. N Engl J Med. 2001;344(3):205–11. PubMed CrossRef Google Scholar 121. Choby BA. Diagnosis and treatment of streptococcal pharyngitis. Am Fam Physician. 2009;79(5):383–90. PubMed Google Scholar 122. Shulman ST, et al. [link.springer.com]
Patients with adenoviral pharyngitis often have pharyngeal exudate, so the disease can mimic streptococcal pharyngitis. [microbiologybook.org]
Because newborns and young infants prefer to breathe through their nose, even moderate nasal congestion can create difficulty breathing. [merckmanuals.com]
The majority of patients in health care settings that present with complaints of runny nose, nasal congestion, cough and headache have a viral upper respiratory infection (the common cold). [healthcentral.com]
Often, the first 2 to 3 days are marked by nasal congestion and stuffiness, followed by several days of sniffling and a runny nose. [care.american-rhinologic.org]
To find relief from nasal congestion, try some extra humidity. Use a humidifier in your room. You can also use a neti pot or saline water for some relief. [ Read: Nasal Congestion Relief During Pregnancy ] 5. [momjunction.com]
The absence of green nasal discharge, the absence of disturbed sleep and mild symptoms were associated with a diagnosis of URI. [ncbi.nlm.nih.gov]
In viral nasopharyngitis patients have profuse nasal discharge, fever, halitosis, mouth breathing leading to dry mouth, hyposmia, sneezing and odynophagia, symptoms that occur 2-3 days after inoculation and last for 7-14 days, depending on the age of [symptoma.com]
Symptoms & Signs In infants :fever, nasal discharge, difficulty feeding, decreased appetite, and difficulty sleeping. In school-aged children:nasal congestion, sneeze, fever, nasal discharge, headache, sore throat, hoarseness and cough 10. [slideshare.net]
Ciprofloxacin 500 mg BD for 7 days If nasal discharge headache or cough persisit antibiotics are indicated. [speciality.medicaldialogues.in]
Accompanying symptoms such as headache, myalgia and nasal obstruction also showed a tendency to decrease. Within 3 days of treatment, six of the eight patients had recovered from the URTI. No adverse effects of acupuncture treatment were reported. [ncbi.nlm.nih.gov]
More severe viral upper respiratory infections also cause vomiting, nausea, diarrhea and abdominal pain, as well as myalgia, fatigue or malaise- more frequent in influenza virus infection. [symptoma.com]
[…] nasal discharge; hoarseness suggests laryngitis; difficulty in swallowing oral secretions and stridor should raise suspicion for epiglottitis or pharyngeal abscess; influenza presents as a sudden illness characterized by high fever, severe headache, myalgia [medical-dictionary.thefreedictionary.com]
Some Infectious Agents that Cause the Common Cold Agents* Human Serotypes Other unique symptoms in addition to coryza Myxoviruses Influenza A, B, C Myalgia and fatigue Parainfluenza 1, 2, 3, 4 Myalgia and fatigue Respiratory syncytial virus 1 (possibly [atsu.edu]
She denies myalgias, shortness of breath, and ear pain, but does admit to mild headache. On physical exam, the nasal mucosa is swollen and erythematous. There is a small amount of whitish discharge inside the left naris. [medicine.uiowa.edu]
The diagnosis of viral upper respiratory tract infection is mostly clinical, but several tests may also be helpful. For instance, the physician may order influenza rapid test, Epstein-Barr heterophile antibody test, cell culture for herpes simplex virus identification  or polymerase chain reaction in order to detect the same type of infection. Epiglottitis can be diagnosed by direct visualization during laryngoscopy, provided that the patient's clinical status allows it. The microbiological specimen is obtained from throat or nasal swabs or washes; they are cultured on special media in order to identify respiratory syncytial virus, influenza and parainfluenza virus and adenovirus. Antibody titers should be observed in a dynamic manner.
The complete blood cell count shows lymphocytosis in acute viral infections, but lymphopenia may also be noticed in some cases. A high white blood cell number is not unusual. In case dyspnea is noticed, foreign body inhalation should be excluded using imaging methods. In croup, the steeple sign representing subglottic stenosis may be noticed . In acute viral otitis media, tympanometry may be useful.
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