Presentation
The observation that a more formed vitreous is present in eyes affected by VMT or MH as observed during pars plana vitrectomy repair by the senior author and the OCT correlation presented in this study support the notion that vitreous degeneration or [ncbi.nlm.nih.gov]
All retinal detachments require emergent ophthalmologic consult. 1 Differentiating between the three conditions often presents a diagnostic quandary because all three may have similar presenting symptoms. [emra.org]
Clinically, paresthesia, sensory ataxia, and sometimes spastic paraplegia are present. The disease is the result of pernicious anemia. vacuolar degeneration Swelling of cells with an increase in the number and size of vacuoles. [medical-dictionary.thefreedictionary.com]
Entire Body System
- Swelling
The disease is the result of pernicious anemia. vacuolar degeneration Swelling of cells with an increase in the number and size of vacuoles. [medical-dictionary.thefreedictionary.com]
- Asymptomatic
The condition is usually bilateral and is often asymptomatic although affected persons may complain of seeing sudden flashes of light. [medical-dictionary.thefreedictionary.com]
- Inflammation
[…] finding in the brain cells of some patients with Alzheimer's dementia in which the neuronal cytoplasm is partly replaced by cavities that contain particles resembling grit or sand. gray degeneration Degeneration in myelinated nerve tissue due to chronic inflammation [medical-dictionary.thefreedictionary.com]
Eyes
- Retinal Pigmentation
In dry MD, the more common and more benign form, hard and soft drusen accumulate beneath the retinal pigment epithelium. They may cause slowly progressive blurring of central vision or may occasionally and gradually lead to wet MD. [medical-dictionary.thefreedictionary.com]
Skin
- Macula
In wet MD, neovascularization intrudes under the retinal pigment epithelium from the choroid, where the new blood vessels may suddenly bleed or leak fluid, distort the normal architecture of the macula, and degrade central visual acuity. [medical-dictionary.thefreedictionary.com]
For each eye, all B-scans through the central macula from both the VMT/MH and control groups were exported. [ncbi.nlm.nih.gov]
Neurologic
- Neglect
However, our understanding of the role of the vitreous body itself in this spectrum of disease has been neglected. [ncbi.nlm.nih.gov]
- Encephalopathy
[…] grit or sand. gray degeneration Degeneration in myelinated nerve tissue due to chronic inflammation, causing the nerve tissue to turn gray. hepatocerebral degeneration Loss of nerve and supporting cells of the brain from multiple episodes of hepatic encephalopathy [medical-dictionary.thefreedictionary.com]
- Ataxia
Clinically, paresthesia, sensory ataxia, and sometimes spastic paraplegia are present. The disease is the result of pernicious anemia. vacuolar degeneration Swelling of cells with an increase in the number and size of vacuoles. [medical-dictionary.thefreedictionary.com]
Workup
Colonoscopy
- Polyps
Nissl degeneration See: Nissl, Franz pigmentary degeneration Degeneration in which affected cells develop an abnormal color. polypoid degeneration Formation of polyp-like growths on mucous membranes. secondary degeneration Wallerian degeneration. senile [medical-dictionary.thefreedictionary.com]
Other Pathologies
- Granulovacuolar Degeneration
degeneration Change of membranous tissue into fibrous tissue. frontotemporal lobar degeneration Pick's disease. granulovacuolar degeneration A pathological finding in the brain cells of some patients with Alzheimer's dementia in which the neuronal cytoplasm [medical-dictionary.thefreedictionary.com]
Treatment
Schedule Eye Exam VISION THERAPY Vision Therapy treatment addresses developmental or acquired visual deficits that impact patients’ daily lives in their academic, sports, and workplace performance. [eyecarespecialties.com]
However, this form of treatment is complicated by a high rate of recurrence and some immediate visual loss in a scotoma. [medical-dictionary.thefreedictionary.com]
In these cases, additional imaging such as Optical Coherence Tomography (OCT) or ocular ultrasound are used. [6] Treatment [ edit ] Therapy is not required or indicated in posterior vitreous detachment, unless there are associated retinal tears, which [en.wikipedia.org]
The implications of this theory may alter the way we think about not only the pathogenesis but also future treatment paradigms of VMT-MH spectrum disorders. [ncbi.nlm.nih.gov]
Etiology
C.. 2010 Oxygen distribution in the human eye: relevance to the etiology of open-angle glaucoma after vitrectomy. Invest. Ophthalmol. Vis. Sci. 51, 5731–5738.doi: 10.1167/iovs.10-5666 ( doi:10.1167/iovs.10-5666 ). [royalsocietypublishing.org]
Prevention
Schedule Contact Lens Exam Prevention and Treatment At EyeCare Specialties, our board-certified doctors use the latest technology to detect and treat eye diseases like cataracts, macular degeneration, and glaucoma. [eyecarespecialties.com]
[…] less noticeable, and eventually most symptoms will completely disappear. [7] Prompt examination of patients experiencing vitreous humor floaters combined with expeditious treatment of any retinal tears has been suggested as the most effective means of preventing [en.wikipedia.org]
However, this study suggests that progression of vitreous degeneration is not a causative factor in vitreoretinal interface disease but may in fact be preventative. [ncbi.nlm.nih.gov]
We suggest that maintaining low pO 2 around the lens should prevent the formation of nuclear cataracts. References 1 Kuszak J. R., Zoltoski R. K.& Tiedemann C. E.. 2004 Development of lens sutures. Int. J. Dev. [royalsocietypublishing.org]