Case reports CASE 1 The patient, now 8 years old, was the first son of a healthy Vietnamese couple with no bleeding history. At the age of 2 years he was admitted to hospital with severe bleeding and platelet count of 25 10 9 /l. [adc.bmj.com]

Despite platelet transfusion a major haemorrhagic episode occurred in our patient after surgery for an inguinal hernia. [adc.bmj.com]

The patients were studied before and after intravenous administration of desmopressin (DDAVP) at doses of 0.4 µg/kg body weight. Automatic sequencing techniques were used to analyze VWF gene exon 28. [link.springer.com]

Laboratory findings showed normal immunoglobulin concentrations, normal leucocyte and erythrocyte counts, and bone marrow aspirate showed a normal number of megakariocytes. [adc.bmj.com]

Four weeks after her last dose of vWF, she complained of heavy vaginal bleeding. She was treated with vWF replacement 60 IU/kg, followed by 30 IU/kg daily for two days. Tranexamic acid was restarted and she achieved good control of her bleeding. [ashclinicalnews.org]