Presentation
One carrier vehicle preferred for use in the present invention is a hydrophilic ointment prepared according to the following Example. [patents.google.com]
Hyperkeratosis may be present. Buy Membership for Obstetrics & Gynecology Category to continue reading. Learn more here Related Netters Obstetrics and Gynecology [clinicalgate.com]
All material presented here is unclassified. C. 2009, 2014, All Rights Reserved [brooksidepress.org]
Definition / general Unrelated disorders of epithelial growth that present as irregular patchy areas of thickened skin and severe itching Types: Squamous cell hyperplasia (most common form) Lichen sclerosus Other dermatoses (e.g. psoriasis and lichen [pathologyoutlines.com]
Skin
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Skin Patch
There are different types of dystrophy that cause white or gray patches of skin, thickening and itchy skin patches, thin areas of skin, or painful sores. [summitmedicalgroup.com]
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Skin Tear
In addition to itching and burning, surface bleeding may also occur because the thin skin tears easily. [wisegeek.com]
Urogenital
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Dyspareunia
[…] and reported dyspareunia and burning sensation after localized burning - observed 2 weeks treatment. stenosis of the vaginal orifice - Discontinuance of the vulvar skin thin, dry, shiny and ointment led to a recur- whitish in appearance - biopsy rence [patents.google.com]
Clinical findings Often asymptomatic; less commonly, itching, dyspareunia, dysuria and tenderness. [medical-dictionary.thefreedictionary.com]
[…] vulva • Fissuring and excoriations (common) Differential Diagnosis • Vulvar cancer (premalignant or malignant changes) • Chronic mycotic vulvitis • Contact vulvitis • Psoriasis • Lichen sclerosus Associated Conditions: Vulvodynia, vulvar pruritus, and dyspareunia [clinicalgate.com]
A 60-year-old widow who recently remarried complains of dyspareunia. [mdedge.com]
Workup
Workup and Evaluation Laboratory: No evaluation indicated. Imaging: No imaging indicated. Special Tests: Biopsy may be required to confirm the diagnosis. Cultures for Candida or other dermatophytes should be considered. [clinicalgate.com]
Therapeutic options will not be discussed here, as these require a consultation and workup with a therapist knowledgeable in diagnosis and therapy of vulvar pain syndromes. [drmichaelgoodman.com]
Differential Diagnosis and Workup Workup and procedures If the diagnosis is not readily apparent, unaided (ie, naked-eye) or colposcopic examination of the vulva may define areas of abnormality that may warrant biopsy using a Keyes punch or biopsy forceps [emedicine.medscape.com]
Treatment
The exact dosage applied in each treatment is not critical since the effective amount may be administered in one or a plurality of treatments. [patents.google.com]
Standard treatments include hormone treatments, herbal medications, laser and microwave exposures, and surgery, but there is a high recurrence rate with all of these. [bermansexualhealth.com]
So far, vulvar carcinoma did not develop in any of the patient followed in our study who received treatment for vulvar dystrophy. [ncbi.nlm.nih.gov]
Prognosis
Vulvar cancer is usually associated with a poor prognosis. [amboss.com]
Grade I (mature, or well-differentiated) cancers have a better prognosis than grade 3 (poorly-differentiated) tumors. [womenscancercenter.com]
In addition, some dysplastic lesions may have a worse prognosis than isolated carcinomas without leukoplakia. However, dysplastic lesions can regress spontaneously. Therefore, the behaviour of dysplastic lesions is unpredictable. [patient.info]
[…] differentiated vulvar intraepithelial neoplasia, lichen planus, cutaneous amyloidosis, malignant melanoma with regression Site vulva, penis, urethra Associated Dx differentiated vulvar intraepithelial neoplasia, vulvar squamous cell carcinoma Symptoms pruritis Prognosis [librepathology.org]
If vulvar cancer has invaded the lymph nodes, the prognosis depends on the number of lymph nodes involved. [drugs.com]
Etiology
Other dermatoses (e.g. psoriasis and lichen planus, skin changes secondary to chronic infections) Often white skin (leukoplakia) but may be red Easily traumatized Suggested to diagnose as dermatosis, not as vulvar dystrophy ( Mod Pathol 1997;10:401 ) Etiology [pathologyoutlines.com]
Vaginal cancer is closely related to vulvar cancer in terms of etiology and histology, but it occurs inside the vagina (typically the posterior third of the vaginal wall), rather than the vulva. [amboss.com]
[…] liſtOOTWämism 105 Chlamydiae 118 Bodily Defenses Against Viral 124 T mimal Paſúsite 137 Nikanna Road 139 Tapeworms 145 HIV and Its Target 161 Treatment of HIV Infection 167 Congenital and Hereditary 177 Jones and Bartlett Publishers International 201 10 207 Etiologic [books.google.de]
In medicine, it might be ideal for classification to be formulated on etiology or pathophysiology (infectious diseases, metabolic diseases, malignant diseases, etc.) but unfortunately information regarding etiology and pathophysiology is not complete [reproductivemedicine.com]
The etiologies of other benign connective tumors in this area are unknown. [emedicine.medscape.com]
Epidemiology
genital lichen planus ( hypertrophied skin with purple lesions) Etiology : unclear (hormonal, immunological, and/or infectious factors are believed to play a role) Epidemiology : postmenopausal women and, less commonly, prepubescent girls Clinical [amboss.com]
Epidemiology Prevalence - the estimated worldwide prevalence is 2% [ 4 ]. Most cases of leukoplakia occur at age 50-70 years. Less than 1% of patients are under the age of 30 years [ 5 ]. [patient.info]
Vulvar cancer: epidemiology, clinical presentation, and management options. Int J Womens Health. 2015 Mar 20;7:305-13. Aragona AM, Cuneo NA, Soderini AH, Alcoba EB. [oncolink.org]
However, firm epidemiological data are lacking for many reasons. Gynecologists and urologists do not generally perform a complete cutaneous examination, and dermatologists often exclude a genital examination. [cirp.org]
Pathophysiology
Current Obstetrics & Gynaecology, 1, 97-102. doi:10.1016/0957-5847(91)90038-Y [ 3 ] Neill, S. and Lewis, F. (2009) Ridley’s the vulva. 3rd Edition, Wiley-Blackwell, Hoboken. [ 4 ] Smith, Y.R. and Haefner, H.K. (2004) Vulvar lichen sclerosus: Pathophysiology [dx.doi.org]
In medicine, it might be ideal for classification to be formulated on etiology or pathophysiology (infectious diseases, metabolic diseases, malignant diseases, etc.) but unfortunately information regarding etiology and pathophysiology is not complete [reproductivemedicine.com]
Etiology and Pathophysiology Nonneoplastic epithelial disorders are discussed below. [emedicine.medscape.com]
Prevention
It is quite possible that this involves the same mechanism which prevents development of adhesions after application of hyaluronic acid following abdominal operations in an animal model [11]. [eurolek.eu]