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Vulvar Dystrophy


Presentation

  • All material presented here is unclassified. C. 2009, 2014, All Rights Reserved[brooksidepress.org]
  • Hyperkeratosis may be present. Buy Membership for Obstetrics & Gynecology Category to continue reading. Learn more here Related Netters Obstetrics and Gynecology[clinicalgate.com]
  • One carrier vehicle preferred for use in the present invention is a hydrophilic ointment prepared according to the following Example.[google.com]
  • Definition / general Unrelated disorders of epithelial growth that present as irregular patchy areas of thickened skin and severe itching Types: Squamous cell hyperplasia (most common form) Lichen sclerosus Other dermatoses (e.g. psoriasis and lichen[pathologyoutlines.com]
Cheilitis
  • Side effects included cheilitis, dryness of mucous membranes and slight loss of hair. It must be taken into account that etretinate may cause liquid metabolism disturbances, particularly among risk factor patients (diabetes, obesity etc.).[ncbi.nlm.nih.gov]
Skin Tear
  • In addition to itching and burning, surface bleeding may also occur because the thin skin tears easily.[wisegeekhealth.com]
Dyspareunia
  • Clinical findings Often asymptomatic; less commonly, itching, dyspareunia, dysuria and tenderness.[medical-dictionary.thefreedictionary.com]
  • […] vulva • Fissuring and excoriations (common) Differential Diagnosis • Vulvar cancer (premalignant or malignant changes) • Chronic mycotic vulvitis • Contact vulvitis • Psoriasis • Lichen sclerosus Associated Conditions: Vulvodynia, vulvar pruritus, and dyspareunia[clinicalgate.com]
  • […] and reported dyspareunia and burning sensation after localized burning - observed 2 weeks treatment. stenosis of the vaginal orifice - Discontinuance of the vulvar skin thin, dry, shiny and ointment led to a recur- whitish in appearance - biopsy rence[google.com]
  • Deep Pelvic Pain and Deep Dyspareunia Patients with chronic level 3 dyspareunia (deep dyspareunia), usually exhibit pain during deep thrust vaginal intercourse.[pelvicurecenter.com]

Workup

  • Workup and Evaluation Laboratory: No evaluation indicated. Imaging: No imaging indicated. Special Tests: Biopsy may be required to confirm the diagnosis. Cultures for Candida or other dermatophytes should be considered.[clinicalgate.com]
  • Therapeutic options will not be discussed here, as these require a consultation and workup with a therapist knowledgeable in diagnosis and therapy of vulvar pain syndromes.[drmichaelgoodman.com]

Treatment

  • Abstract Procedures aimed at the treatment of precancerous lesions and ectopia on the uterine cervix are frequently linked to lesions of anatomical structures.[ncbi.nlm.nih.gov]
  • Standard treatments include hormone treatments, herbal medications, laser and microwave exposures, and surgery, but there is a high recurrence rate with all of these.[bermansexualhealth.com]
  • […] highlights the fact that all cases of vulvar dystrophy especially, lichen sclerosus must be regularly followed up for development of squamous cell hyperplasia and their progression to overt vulvar carcinoma, emphasizing the need for early diagnosis and treatment[ncbi.nlm.nih.gov]
  • So far, vulvar carcinoma did not develop in any of the patient followed in our study who received treatment for vulvar dystrophy.[ncbi.nlm.nih.gov]

Prognosis

  • Vulvar cancer is usually associated with a poor prognosis.[amboss.com]
  • In addition, some dysplastic lesions may have a worse prognosis than isolated carcinomas without leukoplakia. However, dysplastic lesions can regress spontaneously. Therefore, the behaviour of dysplastic lesions is unpredictable.[patient.info]
  • Grade I (mature, or well-differentiated) cancers have a better prognosis than grade 3 (poorly-differentiated) tumors.[womenscancercenter.com]
  • If vulvar cancer has invaded the lymph nodes, the prognosis depends on the number of lymph nodes involved.[drugs.com]
  • […] vulvar intraepithelial neoplasia , lichen planus , cutaneous amyloidosis , malignant melanoma with regression Site vulva , penis , urethra Associated Dx differentiated vulvar intraepithelial neoplasia , vulvar squamous cell carcinoma Symptoms pruritis Prognosis[librepathology.org]

Etiology

  • Other dermatoses (e.g. psoriasis and lichen planus, skin changes secondary to chronic infections) Often white skin (leukoplakia) but may be red Easily traumatized Suggested to diagnose as dermatosis, not as vulvar dystrophy ( Mod Pathol 1997;10:401 ) Etiology[pathologyoutlines.com]
  • Vaginal cancer is closely related to vulvar cancer in terms of etiology and histology, but it occurs inside the vagina (typically the posterior third of the vaginal wall), rather than the vulva .[amboss.com]
  • […] liſtOOTWämism 105 Chlamydiae 118 Bodily Defenses Against Viral 124 T mimal Paſúsite 137 Nikanna Road 139 Tapeworms 145 HIV and Its Target 161 Treatment of HIV Infection 167 Congenital and Hereditary 177 Jones and Bartlett Publishers International 201 10 207 Etiologic[books.google.de]
  • In medicine, it might be ideal for classification to be formulated on etiology or pathophysiology (infectious diseases, metabolic diseases, malignant diseases, etc.) but unfortunately information regarding etiology and pathophysiology is not complete[reproductivemedicine.com]
  • LS, as it is commonly termed, is an insidiously progressive atrophic skin condition of uncertain etiology. It could be genetic, psychogenic, or viral —its cause is really uncertain).[drmichaelgoodman.com]

Epidemiology

  • ., genital lichen planus ( hypertrophied skin with purple lesions) Etiology : unclear (hormonal, immunological, and/or infectious factors are believed to play a role) Epidemiology : postmenopausal women and, less commonly, prepubescent girls Clinical[amboss.com]
  • Epidemiology Prevalence - the estimated worldwide prevalence is 2% [ 4 ] . Most cases of leukoplakia occur at age 50-70 years. Less than 1% of patients are under the age of 30 years [ 5 ] .[patient.info]
Sex distribution
Age distribution

Pathophysiology

  • Current Obstetrics & Gynaecology, 1, 97-102. doi:10.1016/0957-5847(91)90038-Y [ 3 ] Neill, S. and Lewis, F. (2009) Ridley’s the vulva. 3rd Edition, Wiley-Blackwell, Hoboken. [ 4 ] Smith, Y.R. and Haefner, H.K. (2004) Vulvar lichen sclerosus: Pathophysiology[dx.doi.org]
  • In medicine, it might be ideal for classification to be formulated on etiology or pathophysiology (infectious diseases, metabolic diseases, malignant diseases, etc.) but unfortunately information regarding etiology and pathophysiology is not complete[reproductivemedicine.com]

Prevention

  • "FDA Approves Expanded Uses for Gardasil to Include Preventing Certain Vulvar and Vaginal Cancers". 2008-09-12. Retrieved 2010-02-13. External links [ edit ] VIN at DermNet.NZ VIN at Macmillan Cancer Support[en.wikipedia.org]

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