All material presented here is unclassified. C. 2009, 2014, All Rights Reserved [brooksidepress.org]

Hyperkeratosis may be present. Buy Membership for Obstetrics & Gynecology Category to continue reading. Learn more here Related Netters Obstetrics and Gynecology [clinicalgate.com]

One carrier vehicle preferred for use in the present invention is a hydrophilic ointment prepared according to the following Example. [patents.google.com]

Mild hyperkeratosis is present along with epithelial thickening. No nuclear atypia is present. [med-ed.virginia.edu]

• Weakness

  Squamous cell hyperplasia was a weakness of the ISSVD classification. [ijdvl.com]

• Infertility

  Severe cases may be associated with infertility. Although the amount of pain does not always reflect how severe the condition is, recent studies tend to associate the severity of dyspareunia with the severity of the disease. [pelvicurecenter.com]

• Prolapse

  Complications of radical surgery for vulvar cancer include wound breakdown or infection, chronic leg swelling, collection of lymphatic fluid in the groin (lymphocyst), scarring of the vaginal opening, vaginal or uterine prolapse, loss of urine when coughing [womenscancercenter.com]

  Potential associated conditions include: genetic predisposition, combined birth control pills intake, Interstitial cystitis, irritable bowel syndrome, pelvic muscle over-activity, pelvic organ prolapse, fibromyalgia, myofascial dysfunctions (Orofacial [pelvicurecenter.com]

  Red nodules Furuncles (boils) Wart (HPV infection) Prurigo nodularis Vulvar intraepithelial neoplasia (VIN) Molluscum contagiosum (inflamed) Urethral caruncle and prolapse Hidradenitis suppurativa Mammary-like gland adenoma (hidradenoma papilliferum) [womenshealthsection.com]

• Papule

  […] vul·var dys·tro·phy a spectrum of vulvar eruptions consisting of white atrophic papules, including lichen sclerosus et atrophicus, squamous cell hyperplasia (hypertrophic dystrophy), or a combination of these (mixed dystrophy). [medical-dictionary.thefreedictionary.com]

  Definition Lichen sclerosus et atrophicus (LSA) is a chronic skin disease characterized by white, flat papules with an erythematous halo and black, hard follicular plugs. [healthcentral.com]

  These papules grow and multiply and tend to become more widespread and verrucous with age. [emedicine.medscape.com]

  Dystrophies, vulvodynia, and other noncancerous lesions Fast Track Vulvar dystrophies Lichen sclerosus Squamous cell hyperplasia Formerly “hyperplastic dystrophy” Other dermatosis Squamous cell carcinoma in situ May present clinically at any age as papules [mdedge.com]

• Burning Sensation

  Clinical manifestations of vulvar cancer include new lumps or lesions, itching, a burning sensation and, less frequently, vulvar bleeding. [amboss.com]

  > The commonest early symptoms are itching or a burning sensation in the vulval area. What is Lichen Sclerosus ? > It is one of the commonest vulval diseases and is sometimes referred to as Lichen sclerosus et atrophicus. [drraslan.com]

  sensation after localized burning - observed 2 weeks treatment. stenosis of the vaginal orifice - Discontinuance of the vulvar skin thin, dry, shiny and ointment led to a recur- whitish in appearance - biopsy rence of the disease confirmed diagnosis [patents.google.com]

  The C-fibers are relatively primitive, unmyelinated fibers that slowly conduct ill defined aching and burning sensations to the subcortical region of the brain. [pelvicurecenter.com]

• Dyspareunia

  Deep Pelvic Pain and Deep Dyspareunia Patients with chronic level 3 dyspareunia (deep dyspareunia), usually exhibit pain during deep thrust vaginal intercourse. [pelvicurecenter.com]

  […] and reported dyspareunia and burning sensation after localized burning - observed 2 weeks treatment. stenosis of the vaginal orifice - Discontinuance of the vulvar skin thin, dry, shiny and ointment led to a recur- whitish in appearance - biopsy rence [patents.google.com]

  Clinical findings Often asymptomatic; less commonly, itching, dyspareunia, dysuria and tenderness. [medical-dictionary.thefreedictionary.com]

  A 60-year-old widow who recently remarried complains of dyspareunia. [mdedge.com]

• Vaginal Discharge

  C. albicans Gardnerella Trichomonas 42 Vaginitis Vaginal discharge from vaginitis is 1 presenting gynecologic symptom Other presenting sx related to vaginitis dysuria, odor, vulvar burning and pruritis In middle-class, reproductive age women 50 Bacterial [powershow.com]

  Vaginal discharge may be heavier, sticky and/or yellow. If left untreated, lichen planus can cause scarring of the labia, vulva area. [katha-soma.com]

  A speculum examination is necessary to detect vaginal findings such as ulceration, synechiae, loss of rugae, pallor, and petechiae. Vaginal discharge should be obtained for cultures, wet mount, and pH assessment. [womenshealthsection.com]

  Some of the words our patients use to describe their discomfort are: itching burning pain soreness cutting ripping swelling lumps ulcers vaginal discharge. [mydr.com.au]

• Clitoromegaly

  Testosterone s androgenic side affects such as clitoromegaly, hirsutism, voice changes, acne, and dermal hypertrophy may not be accepted by all patients. [rima.org]

Workup and Evaluation Laboratory: No evaluation indicated. Imaging: No imaging indicated. Special Tests: Biopsy may be required to confirm the diagnosis. Cultures for Candida or other dermatophytes should be considered. [clinicalgate.com]

Therapeutic options will not be discussed here, as these require a consultation and workup with a therapist knowledgeable in diagnosis and therapy of vulvar pain syndromes. [drmichaelgoodman.com]

Differential Diagnosis and Workup Workup and procedures If the diagnosis is not readily apparent, unaided (ie, naked-eye) or colposcopic examination of the vulva may define areas of abnormality that may warrant biopsy using a Keyes punch or biopsy forceps [emedicine.medscape.com]

The exact dosage applied in each treatment is not critical since the effective amount may be administered in one or a plurality of treatments. [patents.google.com]

Standard treatments include hormone treatments, herbal medications, laser and microwave exposures, and surgery, but there is a high recurrence rate with all of these. [bermansexualhealth.com]

So far, vulvar carcinoma did not develop in any of the patient followed in our study who received treatment for vulvar dystrophy. [ncbi.nlm.nih.gov]

Grade I (mature, or well-differentiated) cancers have a better prognosis than grade 3 (poorly-differentiated) tumors. [womenscancercenter.com]

Vulvar cancer is usually associated with a poor prognosis. [amboss.com]

In addition, some dysplastic lesions may have a worse prognosis than isolated carcinomas without leukoplakia. However, dysplastic lesions can regress spontaneously. Therefore, the behaviour of dysplastic lesions is unpredictable. [patient.info]

If vulvar cancer has invaded the lymph nodes, the prognosis depends on the number of lymph nodes involved. [drugs.com]

[…] differentiated vulvar intraepithelial neoplasia, lichen planus, cutaneous amyloidosis, malignant melanoma with regression Site vulva, penis, urethra Associated Dx differentiated vulvar intraepithelial neoplasia, vulvar squamous cell carcinoma Symptoms pruritis Prognosis [librepathology.org]

Vaginal cancer is closely related to vulvar cancer in terms of etiology and histology, but it occurs inside the vagina (typically the posterior third of the vaginal wall), rather than the vulva. [amboss.com]

Other dermatoses (e.g. psoriasis and lichen planus, skin changes secondary to chronic infections) Often white skin (leukoplakia) but may be red Easily traumatized Suggested to diagnose as dermatosis, not as vulvar dystrophy ( Mod Pathol 1997;10:401 ) Etiology [pathologyoutlines.com]

[…] liſtOOTWämism 105 Chlamydiae 118 Bodily Defenses Against Viral 124 T mimal Paſúsite 137 Nikanna Road 139 Tapeworms 145 HIV and Its Target 161 Treatment of HIV Infection 167 Congenital and Hereditary 177 Jones and Bartlett Publishers International 201 10 207 Etiologic [books.google.de]

The etiologies of other benign connective tumors in this area are unknown. [emedicine.medscape.com]

[…] architecture Lichen simplex chronicus : squamous cell hyperplasia Other dermatoses, e.g., genital lichen planus ( hypertrophied skin with purple lesions) Etiology : unclear (hormonal, immunological, and/or infectious factors are believed to play a role) Epidemiology [amboss.com]

Epidemiology Prevalence - the estimated worldwide prevalence is 2% [ 4 ]. Most cases of leukoplakia occur at age 50-70 years. Less than 1% of patients are under the age of 30 years [ 5 ]. [patient.info]

Vulvar cancer: epidemiology, clinical presentation, and management options. Int J Womens Health. 2015 Mar 20;7:305-13. Aragona AM, Cuneo NA, Soderini AH, Alcoba EB. [oncolink.org]

However, firm epidemiological data are lacking for many reasons. Gynecologists and urologists do not generally perform a complete cutaneous examination, and dermatologists often exclude a genital examination. [cirp.org]

Current Obstetrics & Gynaecology, 1, 97-102. doi:10.1016/0957-5847(91)90038-Y [ 3 ] Neill, S. and Lewis, F. (2009) Ridley’s the vulva. 3rd Edition, Wiley-Blackwell, Hoboken. [ 4 ] Smith, Y.R. and Haefner, H.K. (2004) Vulvar lichen sclerosus: Pathophysiology [scirp.org]

In medicine, it might be ideal for classification to be formulated on etiology or pathophysiology (infectious diseases, metabolic diseases, malignant diseases, etc.) but unfortunately information regarding etiology and pathophysiology is not complete [reproductivemedicine.com]

Etiology and Pathophysiology Nonneoplastic epithelial disorders are discussed below. [emedicine.medscape.com]

Journal of Reproductive Medicine. 2005;50:807-10. ^ "FDA Approves Expanded Uses for Gardasil to Include Preventing Certain Vulvar and Vaginal Cancers". 2008-09-12. Retrieved 2010-02-13. [en.wikipedia.org]

These steps may also help prevent precancerous changes in the vulva. Treatment The treatment of vulvar cancer depends upon the type of cancer, its stage, and its location. [drugs.com]