Int J Gynecol Cancer 2002;12(5):490-5] against proposed performance indicators to illustrate the deficiencies in current data presentation. [ncbi.nlm.nih.gov]

• Burning Pain

  pain, pruritus, bleeding vulvar ulcers Lichen simplex chronicus is characterized by chronic itching, which provokes persistent scratching of the vulva and so causes lichenification of the skin. [amboss.com]

• Amyloidosis

  KEYWORDS: Amyloidosis; Cytokeratins; LC-MS/MS; Squamous intraepithelial lesion; VIN [ncbi.nlm.nih.gov]

• Trigeminal Neuralgia

  trigeminal neuralgia, type 2 diabetes (on insulin), hypothyroidism and bipolar disorder. I’m not a person who tends to panic because my body always seems to be throwing something at me. This discovery scared me though. [themighty.com]

• Vulvar Irritation

  Other cases of VIN are associated with conditions that cause chronic vulvar irritation such as squamous cell hyperplasia (lichen simplex chronicus), lichen sclerosus or lichen planus. [colposcopycenter.com]

  The following factors have been associated with VIN: HPV (Human Papilloma Virus) HSV-2 (Herpes simplex Virus - Type 2) Smoking Immunosuppression Chronic vulvar irritation Conditions such as Lichen Sclerosus The person may have no symptoms, or local symptomatology [en.wikipedia.org]

  Factors associated with VIN: HPV (human papilloma virus) HSV-2 (herpes simplex virus – type 2) Smoking Immunosuppression Chronic vulvar irritation due to: Lichen sclerosis Squamous cell hyperplasia Atopic dermatitis Psoriasis Eczema Signs and symptoms [ndnr.com]

• Genital Lesions

  Inadequacy of standard treatment of genital lesions in HIV patients. Int J Gynecol Obstet 1994;47:273 35 Spitzer M. Lower genital tract intraepithelial neoplasia in HIV-infected women: Guidelines for evaluation and management. [glowm.com]

Vulvar tissue samples taken prior to imiquimod treatment and 4 weeks after treatment were tested for the presence of HPV. [ncbi.nlm.nih.gov]

Although large, multicentre studies are needed to definitively assess the involvement of HPV in the prognosis of VSCC, most studies have not found clear differences in survival between HPV-associated and HPV-independent tumours. 2012 Blackwell Publishing [ncbi.nlm.nih.gov]

How to help yourself if you have been diagnosed with VIN Stop smoking – it has a direct link with VIN HPV vaccines have shown to decrease the risk of VIN, cervical cancer, and genital warts Treat or manage underlying lichen sclerosus when present The prognosis [allthingsvagina.com]

Vulvar cancer is usually associated with a poor prognosis. [amboss.com]

The prognosis of patients with vulvar cancer is generally good when appropriate treatment is initiated in a timely fashion. [aafp.org]

The patients in this group appear to have a better prognosis than the group of patients with ISCC unrelated to HPV [ 1, 2, 9 ]. The second group (unrelated to HPV) accounts for 2/3 of all ISCCs. [hoajonline.com]

Vulvar intraepithelial neoplasia (VIN) generally can be classified into viral and nonviral etiologies. The histopathologic diagnosis is often separable into basaloid and warty types. [ncbi.nlm.nih.gov]

Although u-VIN is etiologically associated with the human papillomavirus (HPVs) infection, d-VIN represents an alternative HPV negative pathway of vulvar carcinogenesis. In 2004, the u-VIN I category was abandoned and u-VIN II and III were merged. [humpath.com]

[…] in a background of lichen sclerosus and chronic inflammatory dermatoses Risk factors include older age, irritation, inflammation, oxidative and ischemic stress Sites Usually confined to nonhair bearing areas or external sides of atrophic labia minora Etiology [pathologyoutlines.com]

This review describes the relevant aspects of squamous VIN, vulvar Paget's disease and melanoma in situ, its epidemiological characteristics, diagnosis, management and malignant potential. [ncbi.nlm.nih.gov]

This may be the result of improved surveillance and treatment of VIN, or the apparent increase in cases of VIN in younger women. 3 Etiology and Pathophysiology VIN is the associated preneoplastic condition that is associated with the loss of epithelial [basicmedicalkey.com]

The goal is to prevent development of invasive vulvar cancer while preserving normal vulvar anatomy and function. The authors describe the case of a 37-year-old woman affected by a biopsy-proven VIN 3 involving the entire external genitalia. [ncbi.nlm.nih.gov]