The specific surgical procedures performed will depend upon the severity and location of the anatomical abnormalities, their associated symptoms, and other factors. [rarediseases.org]

Chronic constipation recognized as a sign of a SOX10 mutation in a patient with Waardenburg syndrome. Gene. 2014;540(2):258-62. Jelena B, Christina L, Eric V, Fabiola QR. [rarediseases.org]

Affiliated tissues include eye and skin, and related phenotypes are sensorineural hearing impairment and heterochromia iridis Disease Ontology : 12 A Waardenburg's syndrome characterized by pigmentary abnormalities of the hair, skin, and eyes, congenital [malacards.org]

WS2 differs from type 1 and some other types of WS by the absence of dystopia canthorum (lateral displacement of the inner canthi of the eyes). 0002216 30%-79% of people have these symptoms Heterochromia iridis Different colored eyes 0001100 Hypopigmented [rarediseases.info.nih.gov]

As a result, affected individuals may have unusually pale blue eyes or differences in the pigmentation of the two irides or within different areas of the same iris (heterochromia irides). [rarediseases.org]

Affiliated tissues include eye and skin, and related phenotypes are sensorineural hearing impairment and heterochromia iridis Disease Ontology : 12 A Waardenburg's syndrome characterized by pigmentary abnormalities of the hair, skin, and eyes, congenital [malacards.org]

[…] of dystopia canthorum (lateral displacement of the inner canthi of the eyes). 0002216 30%-79% of people have these symptoms Heterochromia iridis Different colored eyes 0001100 Hypopigmented skin patches Patchy loss of skin color 0001053 Sensorineural hearing [rarediseases.info.nih.gov]

Some affected individuals may also have hearing impairment due to abnormalities of the inner ear (sensorineural deafness). [rarediseases.org]