Each chromosome has a short arm designated as “p” and a long arm identified by the letter “q.” Chromosomes are further subdivided into bands that are numbered. Therefore, “chromosome 2q35” refers to band 35 on the long arm of chromosome 2. [rarediseases.org]

Synonyms WAARDENBURG SYNDROME WITH DYSTOPIA CANTHORUM Classification developmental, eye, genetic, otorhinolaryngological, skin Phenotypes Aplasia of the vagina ; Autosomal dominant inheritance ; Blepharophimosis ; Blue irides ; Congenital sensorineural hearing [mousephenotype.org]

Treatment or Management of the Condition There are no treatments of the syndrome; however, hearing aids maybe needed for some individuals and maybe some sort of schooling for the hearing impaired individuals. [wiki.ggc.edu]

For example, a person with WS may have a white forelock, a patch of white hair near the forehead, and no hearing impairment. Others may have white patches of skin and severe hearing impairment. [healthfully.org]

Family history revealed hearing impairment in the elder sister and premature graying of the frontal hair with a broad nasal root in both the siblings and the mother. [tjmrjournal.org]

graying of the hair (by age 30) Waardenburg syndrome type 2 is defined as having all the features of type 1 except dystopia canthorum. 77% of individuals with type 2 have hearing loss. [verywell.com]

graying of the hair (before age 30). [escholarship.org]

Signs and Symptoms Deafness (bilateral or unilateral) White patches in the skin Premature graying of the hair Presence of white locks of hair Heterochromia- the color of the eyes do not match Wide set eyes (hypertelorism) A prominent square jaw Eyebrows [syndromespedia.com]

Minor criteria include skin hypopigmentation (congenital leukoderma/ white skin patches), medial eyebrow flare (synophrys), broad nasal root, hypoplasia alae nasi, and premature graying of the hair. [panafrican-med-journal.com]

[…] symbols: HUP2, WS1 ) Mouse Orthologs Pax3 (Withdrawn symbols: Pax-3, Sp, Splchl2 ) Source OMIM:193500 (names, synonyms, disease associated genes), Orphanet (disease classes), HGNC, Ensembl, MGI (gene symbols, gene orthology) HPO (phenotypes) Mouse Models [mousephenotype.org]

Distraction test was not heard in either ear. [tjmrjournal.org]

Physical examination revealed characteristic sapphire-blue irises, dystopia canthorum, high broad nasal root, synophrys, low anterior hairline, mild frontal bossing and deaf-mutism (Fig. 1). [escholarship.org]