Arteriovenous malformations are often the most debilitating of the PWS triad, causing a wide variety of clinical features such as pain, fatigue, ulceration, and high-output congestive heart failure. [interventionalnews.com]

Arteriovenous malformations are often the most debilitating of the PWS triad, causing a wide variety of clinical features such as pain, fatigue, ulceration, and high-output congestive heart failure. [interventionalnews.com]

Our depth of experience in Sturge-Weber syndrome Sturge-Weber syndrome can involve a range of complications, including seizures, developmental delays, muscle weakness and eye problems. [childrenshospital.org]

Affected individuals may also experience muscle weakness or paralysis on one side of the body (hemiparesis), usually on the side opposite the port-wine birthmark. [rarediseases.org]

Occasionally the substantia nigra can also be involved 5. ipsilateral CN III palsy diplopia ptosis afferent pupillary defect contralateral hemiplegia or hemiparesis involvement of the corticospinal and.or corticobulbar tracts contralateral parkinsonian [radiopaedia.org]

J Pediatr Ophthalmol Strabismus 1992;29:349-56. Awad AH, Mullaney PB, Al-Mesfer S, et al. Glaucoma in Sturge-Weber syndrome. J AAPOS 1999;3:40-5. 6.0 6.1 6.2 6.3 Pascual-Castroviejo I, Díaz-Gonzalez C, García-Melian RM, et al. [eyewiki.org]

In a study of 76 patients, Bebin and Gomez reported partial seizures in 35 patients (46%), generalized seizures in 15 of them (20%), and both in 26 of them (34%). [37] Pascual-Castroviejo et al reported seizures in 32 (80%) of 40 patients with SWS; 22 [emedicine.medscape.com]

Seizures in SWS usually start as partial or focal seizures that can spread to a generalized seizure. [epilepsy.com]

Infants who have seizures before the age of 2 years may also have learning difficulties. Glaucoma Regular eye tests can assess for glaucoma, which is more likely with Sturge-Weber syndrome. [medicalnewstoday.com]

Seizures result from cortical irritability caused by cerebral angioma, through mechanisms of hypoxia, ischemia, and gliosis. Dual pathology, such as microgyria, also may be present, which also contributes to epileptogenesis. [emedicine.medscape.com]