Major clinical signs include weight loss (often accompanied by an increased appetite), anxiety, intolerance to heat, fatigue, hair loss, weakness, hyperactivity, irritability, apathy, depression, polyuria, polydipsia, delirium, and sweating. [howlingpixel.com]

Those with dysphagia often require measures to reduce oral secretions, use of thickened liquids and pureed foods to avoid aspiration, and eventually a gastrostomy to help maintain caloric intake. [ncbi.nlm.nih.gov]

Variegate porphyria Carnitine-acylcarnitine translocase deficiency King Denborough syndrome N syndrome Periventricular heterotopia Naxos disease Alpha-1 antitrypsin deficiency Methionine adenosyltransferase deficiency Myoglobinuria recurrent Congenital anosmia [checkrare.com]

Additionally, patients may present with a variety of symptoms such as palpitations and arrhythmias (notably atrial fibrillation), shortness of breath (dyspnea), loss of libido, nausea, vomiting, and diarrhea. [howlingpixel.com]

Chronic diarrhea, including steatorrhea (fatty stools) Pain in the esophagus, especially between and after meals at night Nausea Wheezing Vomiting blood Malnourishment Loss of appetite Gastrinomas may occur as single tumors or as multiple small tumors [maria-online.com]

[…] to thrive-kyphoscoliosis Auriculoosteodysplasia Aplasia cutis congenita of limbs recessive Epidermolysis bullosa simplex, Dowling-Meara type Waardenburg syndrome type 3 Antecubital pterygium Osteoporosis-pseudoglioma syndrome Hypomelanosis of Ito Porokeratosis [checkrare.com]

Zollinger-Ellison syndrome: Signs and symptoms Patients with Zollinger–Ellison syndrome may experience abdominal pain and diarrhea. [maria-online.com]

The syndrome is characterized by alopecia, mental retardation, hypogonadism, diabetes mellitus, hearing impairment, ECG changes, and by autosomal recessive inheritance. [ncbi.nlm.nih.gov]

@article{8509666, abstract {Woodhouse Sakati syndrome (WSS, MIM 241080) is a rare autosomal recessive genetic condition characterized by alopecia, hypogonadism, hearing impairment, diabetes mellitus, learning disabilities and extrapydamidal manifestations [biblio.ugent.be]

impairment 0000407 Sparse hair 0008070 Showing of 38 Last updated: 5/1/2019 If you need medical advice, you can look for doctors or other healthcare professionals who have experience with this disease. [rarediseases.info.nih.gov]

Alopecia, neuropathy, endocrinopathy (ANE) syndrome (OMIM 612079 ) 3 RBM28 AR Hypogonadotropic hypogonadism, alopecia, adrenal insufficiency and cognitive impairment Hutchinson-Gilford progeria syndrome LMNA AD 4 Alopecia, aged-looking skin, joint abnormalities [ncbi.nlm.nih.gov]

Disorder, Progressive, With Primary Hypogonadism, Mental Retardation, and Alopecia Hypogonadism, Alopecia, Diabetes Mellitus, Mental Retardation, Deafness, and Extrapyramidal Syndrome edit English Woodhouse–Sakati syndrome Woodhouse-Sakati syndrome is [wikidata.org]

The syndrome is characterized by alopecia, hypogonadism, hypothyroidism, hearing loss, mental retardation and diabetes mellitus. Electrocardiogram anomalies have also been reported. [eurobuch.com]

The increase in acidity contributes to the development of peptic ulcers in the stomach, duodenum (first portion of the small bowel) and occasionally the jejunum (second portion of the small bowel)-- the last of which is an 'atypical' ulcer. [maria-online.com]

Velikonja T Results of 200 stapled hemorrhoidectomies 2003 Omejc M ; Omejc H ; Štor Z ASA score as an independent prognostic factor in patients with colorectal cancer 2003 Repše S ; Jelenc F ; Čalič M ; Žakelj B ; Omejc M ; Juvan R Surgical treatment of ulcerative [ricinus2.mf.uni-lj.si]

Additional manifestations may include sensorineural deafness, flattened T waves on ECG, seizures, sensory polyneuropathy, dysarthria, various craniofacial abnormalities (high forehead, flat occiput, triangular face, prominent nasal root, hypertelorism [orpha.net]

Other manifestations are very diverse: sensorineural hearing loss, T waves flattened ECG, convulsions, sensory polyneuropathy, a dysarthria ( dysphagia), various craniofacial anomalies (high forehead, flattened occiput, triangular face, prominent nasal [sites.uclouvain.be]

She had dysmorphic facial features including a triangular shape with a large forehead, sparse eyebrows and eyelashes, alopecia predominant in the fronto-temporal region of the scalp, hypertelorism, large ears, prominent nasal root, precocious skin aging [cags.org.ae]

There may be various craniofacial abnormalities such as a high forehead, flat occiput, triangular face, prominent nasal root, hypertelorism which is an abnormally increased distance between the eyes, and down-slanting palpebral fissures. [nbiacanada.com]

In all studied male patients, there was an absence of secondary sexual characteristics with cryptorchidism. Abnormal hormonal levels in the form of low testosterone levels were observed in only three of seven (43%) of our male patients. [journals.lww.com]

One male had cryptorchidism [ Rachmiel et al 2011 ]. Although the testes are of normal size, testicular biopsy reveals reduced spermatogenesis with predominance of Sertoli cells and few Leydig cells [ Woodhouse & Sakati 1983 ]. [ncbi.nlm.nih.gov]

[…] syndrome Congenital central hypoventilation syndrome Alternating hemiplegia of childhood Carpenter syndrome Ehlers-Danlos syndrome, periodontitis type Timothy syndrome Myokymia with neonatal epilepsy Hyperthermia induced defects Torticollis keloids cryptorchidism [checkrare.com]

instability Brain iron accumulation on MRI Dystonia See footnote 7 AD AR XL Variable phenotype ; hypogonadism & alopecia not observed Deafness and hereditary hearing loss See footnote 8 AD AR XL mtDNA Variable phenotype w/variable age of onset; hypogonadism [ncbi.nlm.nih.gov]

problems (almost exclusively in males) Neurodegeneration with brain iron storage disorders PANK2 PLA2G6 C19orf12 FA2H ATP13A2 WDR45 COASY FTL CP AR XL AD 6 Variable phenotype : variable age of onset, dystonia w/postural instability Brain iron accumulation [ncbi.nlm.nih.gov]