It can present in an otherwise asymptomatic patient without any constitutional symptoms. Careful examination, prompt diagnosis, and early treatment can reduce ocular morbidity. [ncbi.nlm.nih.gov]

Author: Ankur Ahuja, DM, 02/17/2020 Category: Infectious Disease > Parasites > Filarasis > Wucheria bancrofti Published Date: 02/18/2020 Download Set 54 years old male a known case of CML presented with fever presented in Accident and Emergency. [imagebank.hematology.org]

• Weight Gain

  The weight difference was attributed to ingested blood. Conversion of the average weight gain to volume was achieved by dividing the weight gain by the specific gravity of blood (1.05 mg.mm3 -1 ). [scielo.br]

• Noncompliance

  Furthermore, a trend toward reduced infection rates in noncompliant people was observed after several rounds of MDA, as this antifilarial medication indirectly benefits noncompliant people by a herd treatment effect [37]. [kamj.eg.net]

• Hunting

  Hunt MR, Chung R, Durocher E, Henrys JH. Haitian and international responders' and decision-makers' perspectives regarding disability and the response to the 2010 Haiti earthquake. Glob Health Action. 2015;8(1):27969. [ Links ] 14. [scielo.br]

• Pleural Effusion

  Aggarwal J, Kapila K, Gaur A, Wali JP: Bancroftian filarial pleural effusion. Postgrad Med J 1993;69:869–870. Kapila K, Verma K: Gravid adult female worms of Wuchereria bancrofti in fine needle aspirates of soft tissue swellings. [karger.com]

• Retinal Pigmentation

  Indirect ophthalmoscopy showed vitritis with plenty of vitreous membranes, and subretinal yellow lesions in the peripheral retina along with retinal pigment epithelial tracts. [ncbi.nlm.nih.gov]

• Corneal Edema

  Persistent corneal edema secondary to presumed dead adult filarial worm in the anterior chamber. Indian J Ophthalmol 2007;55:67-9. [PUBMED] 8. Wright RE. Adult filaria (Wuchreria) Bancrofti in the anterior chamber. Br J Ophthalmol 1934;18:646-50. 9. [tjmrjournal.org]

• Headache

  Sometimes lymphangitis is severe and is accompanied by high fever and headache. In addition to lymphatic involvement, some patients may show epididymitis and orchitis. In the intervening period, repeated attacks of acute lymphangitis may continue. [atlas.or.kr]

  When present, symptoms include fever, angioedema, headache, myalgias, arthralgias, pruritus, and neurologic manifestations. [mayomedicallaboratories.com]

  Lymphatic filariasis (a) Early infection: Patients experience fever, lymphangitis, headaches, nausea and urticaria. (b) Chronic infection: Repeated attacks cause lymphatic damage. 1. [biology-today.com]

  It has some side effects which include: dizziness, fever, headache, nausea and muscle and joint pain. DEC should only be used, if Wuchereria bancrofti has been identified. This is because most people with lymphedema are not infected with parasites. [parasitesinhumans.org]

  Filariasis is characterized by fever, chills, headache, and skin lesions in the early stages and, if untreated, can progress to include gross enlargement of the limbs and genitalia in a condition called elephantiasis. [broadinstitute.org]

[…] affecting humans and animals, caused by filariae; ie, nematode parasites of the family Filariidae. [1] Filarial parasites can be classified according to the habitat of the adult worms in the vertebral host, as follows (see Pathophysiology, Etiology, and Workup [emedicine.medscape.com]

• Mediastinal Mass

  This report concerns an Egyptian man who developed superior vena cava syndrome secondary to a mediastinal mass that was found to contain a filarial nematode consistent with W. bancrofti. [ncbi.nlm.nih.gov]

• Pleural Effusion

  Aggarwal J, Kapila K, Gaur A, Wali JP: Bancroftian filarial pleural effusion. Postgrad Med J 1993;69:869–870. Kapila K, Verma K: Gravid adult female worms of Wuchereria bancrofti in fine needle aspirates of soft tissue swellings. [karger.com]

We assessed treatment efficacy by monitoring microfilaraemia, antigenaemia, and ultrasound detection of adult worms. Follow-up assessments were done at 5, 8, 11, and 14 months after the start of treatment. Analysis was per protocol. [ncbi.nlm.nih.gov]

By fitting a mathematical model of treatment effects to the trial data, we quantified the efficacy of treatment, distinguishing between the killing of mf (mf loss) and a reduction in mf production by adult worms (worm‐productivity loss). [doi.org]

[…] may result in a worse prognosis. [dovemed.com]

Prognosis The prognosis in filariasis is good if infection is recognized and treated early. Filarial diseases are rarely fatal, but the consequences of infection can cause significant personal and socioeconomic hardship for those who are affected. [emedicine.medscape.com]

(Etiology) Wuchereria Bancrofti Infection is caused by an infection of the parasitic nematode (worm), Wuchereria bancrofti. The worms are transmitted from an infected individual to an uninfected individual through mosquito bites. [dovemed.com]

Primary lymphedema is associated with congenital malformations of the lymphatic system, and secondary lymphedema develops from known etiologies. [orlandomedicalnews.com]

We want to stress that in the tropics where filariasis is endemic, it may be worthwhile to rule out filariasis in all cases of uveitis of obscure etiology. [tjmrjournal.org]

(See Pathophysiology and Etiology.) [13] As with most helminths, adult filarial parasites replicate in a definitive host. The adult worm burden in an individual cannot increase unless the host is exposed to additional microfilaria. [emedicine.medscape.com]

Earlier studies have revealed differing epidemiology of LF in the North and South of Ghana. This study was therefore aimed at understanding the possible impacts of W. bancrofti diversity on the epidemiology and control of LF in Ghana. [ncbi.nlm.nih.gov]

Further studies are however required for an in-depth understanding of LF epidemiology and control. [panafrican-med-journal.com]

Useful For Suggests clinical disorders or settings where the test may be helpful Detection of microfilariae in peripheral blood Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test [mayomedicallaboratories.com]

Pathophysiology The filarial life cycle, like that of all nematodes, consists of 5 developmental (larval) stages in a vertebral host and an arthropod intermediate host and vector. [emedicine.medscape.com]

BACKGROUND: Once interruption of transmission of lymphatic filariasis is achieved, morbidity prevention and management becomes more important. [ncbi.nlm.nih.gov]

Wuchereria Bancrofti Infection is best prevented through reducing exposure to mosquito bites. [dovemed.com]

They can apply insect repellants in their skins, use mosquito nets when they sleep especially at night, and do any other preventive methods recommended by experts. [healthguideinfo.com]