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Wuchereria Bancrofti

Filaria Bancrofti


Presentation

  • It can present in an otherwise asymptomatic patient without any constitutional symptoms. Careful examination, prompt diagnosis, and early treatment can reduce ocular morbidity.[ncbi.nlm.nih.gov]
  • The present study was undertaken in Teressa Island to understand the density dependent parasite mortality and survival probability of the parasite Do. nivea.[ncbi.nlm.nih.gov]
  • Immunological studies and interventional treatment studies that eliminate the adult worms and not only the microfilariae are needed to follow up on the results presented.[ncbi.nlm.nih.gov]
  • We present data from molecular and electron microscopic studies to provide evidence for Wolbachia symbiosis in W. bancrofti microfilariae collected from two districts (Bankura and Birbhum) of West Bengal, India.[ncbi.nlm.nih.gov]
  • […] family Onchocercidae genus Wuchereria species Wuchereria bancrofti (Cobbold, 1877) Providers NZAC NZIB Provider Contribution Summary Biostatus Geo Schema Political Region Geo Region New Zealand Biome Terrestrial Environmental Context Wild Occurrence Present[nzor.org.nz]
Constitutional Symptom
  • It can present in an otherwise asymptomatic patient without any constitutional symptoms. Careful examination, prompt diagnosis, and early treatment can reduce ocular morbidity.[ncbi.nlm.nih.gov]
  • However, rarely it can present as intraocular filariasis in an otherwise asymptomatic patient without any constitutional symptoms.[tjmrjournal.org]
Rigor
  • Therefore, rigorous surveillance is still warranted so that LF transmission in Conakry would be identified rapidly and adequate responses being implemented.[ncbi.nlm.nih.gov]
Urticaria
  • Lymphatic filariasis (a) Early infection: Patients experience fever, lymphangitis, headaches, nausea and urticaria. (b) Chronic infection: Repeated attacks cause lymphatic damage. 1.[biology-today.com]
Retinal Pigmentation
  • Indirect ophthalmoscopy showed vitritis with plenty of vitreous membranes, and subretinal yellow lesions in the peripheral retina along with retinal pigment epithelial tracts.[ncbi.nlm.nih.gov]
Headache
  • Sometimes lymphangitis is severe and is accompanied by high fever and headache. In addition to lymphatic involvement, some patients may show epididymitis and orchitis. In the intervening period, repeated attacks of acute lymphangitis may continue.[atlas.or.kr]
  • It has some side effects which include: dizziness, fever, headache, nausea and muscle and joint pain. DEC should only be used, if Wuchereria bancrofti has been identified. This is because most people with lymphedema are not infected with parasites.[parasitesinhumans.org]
  • Lymphatic filariasis (a) Early infection: Patients experience fever, lymphangitis, headaches, nausea and urticaria. (b) Chronic infection: Repeated attacks cause lymphatic damage. 1.[biology-today.com]
  • The most common adverse events among the participants who had an adverse event of grade 2 or 3 were headache, fatigue, and nausea ( Table 3 ).[nejm.org]

Workup

Mediastinal Mass
  • This report concerns an Egyptian man who developed superior vena cava syndrome secondary to a mediastinal mass that was found to contain a filarial nematode consistent with W. bancrofti.[ncbi.nlm.nih.gov]

Treatment

  • We assessed treatment efficacy by monitoring microfilaraemia, antigenaemia, and ultrasound detection of adult worms. Follow-up assessments were done at 5, 8, 11, and 14 months after the start of treatment. Analysis was per protocol.[ncbi.nlm.nih.gov]
  • To visualize the adult worm and monitor the macrofilaricidal effectiveness of DEC treatment, ultrasound examinations of the scrotal area were performed before, during, and for 6 months after treatment.[ncbi.nlm.nih.gov]
  • Blood samples were collected at pre-treatment in 1998, at 1 week and 6 months after the first treatment and thereafter before subsequent treatments in 1999 and 2000.[ncbi.nlm.nih.gov]
  • BACKGROUND: Annual mass treatment with albendazole and ivermectin is the mainstay of current strategies to interrupt transmission of Wuchereria bancrofti in Africa.[ncbi.nlm.nih.gov]
  • CONCLUSION: 7 years of annual mass treatment with ivermectin monotherapy for onchocerciasis did not interrupt LF transmission.[ncbi.nlm.nih.gov]

Prognosis

Etiology

  • (Etiology) Wuchereria Bancrofti Infection is caused by an infection of the parasitic nematode (worm), Wuchereria bancrofti. The worms are transmitted from an infected individual to an uninfected individual through mosquito bites.[dovemed.com]
  • We want to stress that in the tropics where filariasis is endemic, it may be worthwhile to rule out filariasis in all cases of uveitis of obscure etiology.[tjmrjournal.org]

Epidemiology

  • Earlier studies have revealed differing epidemiology of LF in the North and South of Ghana. This study was therefore aimed at understanding the possible impacts of W. bancrofti diversity on the epidemiology and control of LF in Ghana.[ncbi.nlm.nih.gov]
  • Then, we provide a perspective to aid in understanding how population genetic techniques translate to modern epidemiology. Finally, we introduce the concept of genomic epidemiology and provide some examples that will aid in future studies of Wb.[ncbi.nlm.nih.gov]
  • Filariasis/parasitology* Helminth Proteins/chemistry Helminth Proteins/genetics* Helminth Proteins/immunology Humans India/epidemiology Microfilariae/genetics Microfilariae/immunology Molecular Sequence Data Phylogeny Polymerase Chain Reaction Polymorphism[ncbi.nlm.nih.gov]
  • Abstract Lymphatic filariasis has been considered as a disease of adults and most epidemiological surveys have excluded children.[ncbi.nlm.nih.gov]
  • Important biological and epidemiological aspects are also described including the lifecycle of each parasite species and their specificities, the geographical biodiversity of each pathogen and their vectors where the parasites are co-endemic, and biological[ncbi.nlm.nih.gov]
Sex distribution
Age distribution

Pathophysiology

  • Useful For Suggests clinical disorders or settings where the test may be helpful Detection of microfilariae in peripheral blood Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test[mayomedicallaboratories.com]

Prevention

  • BACKGROUND: Once interruption of transmission of lymphatic filariasis is achieved, morbidity prevention and management becomes more important.[ncbi.nlm.nih.gov]
  • They can apply insect repellants in their skins, use mosquito nets when they sleep especially at night, and do any other preventive methods recommended by experts.[healthguideinfo.com]
  • Wuchereria Bancrofti Infection is best prevented through reducing exposure to mosquito bites.[dovemed.com]

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