Presentation
Some are non-syndromic while in others, a syndromic phenotype is present. [latunisiemedicale.com]
Entire Body System
- Disability
Systematic phenomics analysis deconvolutes genes mutated in intellectual disability into biologically coherent modules.Am J Hum Genet. 2016;98(1):149-64. [ Links ] 45. Jamra R. Genetics of autosomal recessive intellectual disability. [scielo.org.pe]
This disability originates before the age of 18 years. Although not perfect, the intellectual criterion for the diagnosis of MR is often represented by a Full Scale Intelligence Quotient of 70 or less. [latunisiemedicale.com]
Treatment
In addition to pharmaceutical intervention, one should not forget the positive effects that can be obtained by conventional ‘treatment’, offering MR individuals a stimulating and activating environment. [latunisiemedicale.com]
Intellectual disability: definition, etiological factors, classification, diagnosis, treatment and prognosis. Salud Pública México. 2008;50:132-41. [ Links ] 29. Maulik PK, Darmstadt GL. [scielo.org.pe]
Prognosis
Intellectual disability: definition, etiological factors, classification, diagnosis, treatment and prognosis. Salud Pública México. 2008;50:132-41. [ Links ] 29. Maulik PK, Darmstadt GL. [scielo.org.pe]
Etiology
Intellectual disability: definition, etiological factors, classification, diagnosis, treatment and prognosis. Salud Pública México. 2008;50:132-41. [ Links ] 29. Maulik PK, Darmstadt GL. [scielo.org.pe]
Epidemiology
Childhood disability in low- and middle-income countries: Overview of screening, prevention, services, legislation, and epidemiology. Pediatrics. 2007;120 (Supplement 1):S1-55. [ Links ] 30. Mercadante MT, Evans-Lacko S, Paula CS. [scielo.org.pe]
Pathophysiology
The pathophysiological processes of MR in the human brain are very complex and, have most probably started already in early pregnancy. [latunisiemedicale.com]
Prevention
Prevention of intellectual and developmental disabilities. Intellect Dev Disabil. 2009; 47(4):320-2. [ Links ] 79. Calderón-González R, Calderón-Sepúlveda RF. Prevention of mental retardation. Rev Neurol. 2003;36(2):184-94. [ Links ] 80. [scielo.org.pe]