A 23-year-old woman presented with a 9-month history of polydipsia, polyuria, galactorrhea, secondary amenorrhea, and weightgain. Her previous medical history included chronic anemia and widespread mucocutaneous xanthomas.[ncbi.nlm.nih.gov]
Results: A 23-year-old woman presented with a 9-month history of polydipsia, polyuria, galactorrhea, secondary amenorrhea, and weightgain. Her previous medical history included chronic anemia and widespread mucocutaneous xanthomas.[journals.aace.com]
Case: A 16-year-old female patient admitted to our hospital with the complaints of amenorrhoea, weightgain, polidipsia, poliuria, yellow-brownish papular lesions on the cervical, periorbital, axillary and genital regions.[endocrine-abstracts.org]
A 23-year-old woman presented with a 9-month history of polydipsia, polyuria, galactorrhea, secondary amenorrhea, and weight gain. Her previous medical history included chronic anemia and widespread mucocutaneous xanthomas.[ncbi.nlm.nih.gov]
Results: A 23-year-old woman presented with a 9-month history of polydipsia, polyuria, galactorrhea, secondary amenorrhea, and weight gain. Her previous medical history included chronic anemia and widespread mucocutaneous xanthomas.[journals.aace.com]
The underarm lesions and inguinallesions had improved significantly. He had no new lesions develop during follow-up. After 6 months of follow-up, the lesions continued to flatten, with involution of the XD lesions and no evidence of new lesions.[jamanetwork.com]
Vietnamese - English Vietnamese - VietnameseVietnamese - French French - Vietnamese Computing English - English Chinese - Vietnamese Search in: Word Vietnamese keyboard: Off Virtual keyboard: Show English - English (Wordnet) dictionary xanthoma disseminatum[vdict.com]
Laryngoscopy was done and revealed small, yellow-colored nodules on laryngeal mucosa and on both vocal cords which showed limitedmobility.[jpgmonline.com]
A 10-year-old boy was admitted to the University Hospital complaining of exhaustion, night sweats, coughing and dyspnea. Physical examination, laboratory findings and histopathological examination led to the diagnosis of Xanthoma disseminatum.[ncbi.nlm.nih.gov]
He had a sorethroat and severe hoarseness of his voice. There was also infiltration of the pituitary stalk, adenoids, and soft palate. The patient's lipid profile results showed a high triglyceride level.[jamanetwork.com]
A 10-year-old boy was admitted to the University Hospital complaining of exhaustion, nightsweats, coughing and dyspnea. Physical examination, laboratory findings and histopathological examination led to the diagnosis of Xanthoma disseminatum.[ncbi.nlm.nih.gov]
Adverse effects of 2-CdA were limited to joint pain and nightsweats. After 5 treatment cycles, the patient had no new lesions and had achieved additional improvement in established lesions, which were more flat and less erythematous.[jamanetwork.com]
Treatment was initiated with cabergoline, nasally administered desmopressin, radio-frequency ablation of facialskinlesions, and surgical excision of other accessible lesions.[ncbi.nlm.nih.gov]
Skin lesions were accompanied by blurredvision and hoarseness of voice. Examination revealed xanthomatous infiltration of cornea, oral, pharyngeal, and laryngeal mucosae.[ncbi.nlm.nih.gov]
Patients present with characteristic mucocutaneous lesions, diabetes insipidus, dysphagia, dyspnea, hoarseness of voice, and blurredvision.[orpha.net]
Ocular examination revealed conjunctival and left cornealinfiltration by yellow minute papules with normal visual field. Abdomino-pelvic ultrasonography, chest X-ray, upper and lower gastrointestinal endoscopy revealed no abnormality.[jpgmonline.com]
A 23-year-old woman presented with a 9-month history of polydipsia, polyuria, galactorrhea, secondary amenorrhea, and weight gain. Her previous medical history included chronic anemia and widespread mucocutaneous xanthomas.[ncbi.nlm.nih.gov]
Additional findings were polyuria, polydipsia, and amenorrhea. Skin biopsy and electron microscopy results confirmed the diagnosis of XD. The patient was treated with fenofibrate, simvastatin, desmopressin, and sex-hormone replacement therapy.[karger.figshare.com]
Results: A 23-year-old woman presented with a 9-month history of polydipsia, polyuria, galactorrhea, secondary amenorrhea, and weight gain. Her previous medical history included chronic anemia and widespread mucocutaneous xanthomas.[journals.aace.com]
A 23-year-old woman presented with a 9-month history of polydipsia, polyuria, galactorrhea, secondaryamenorrhea, and weight gain. Her previous medical history included chronic anemia and widespread mucocutaneous xanthomas.[ncbi.nlm.nih.gov]
Results: A 23-year-old woman presented with a 9-month history of polydipsia, polyuria, galactorrhea, secondaryamenorrhea, and weight gain. Her previous medical history included chronic anemia and widespread mucocutaneous xanthomas.[journals.aace.com]
Progress logically from the histologic pattern, through the appropriate workup, around the pitfalls, to the best diagnosis.[books.google.it]
A thorough workup is essential to identify the underlying condition in order to initiate early treatment and to prevent later complications.[austinpublishinggroup.com]
The macroscopic lesions arise from phagocytosis in the dermis of plasma lipoproteins that leak from capillaries. 1 Laboratory workup is mandatory to exclude diabetes, nephrotic syndrome, or hypothyroidism.[hkmj.org]
Chest x-rays showed hyperaeration and segmental atelectasis. High-resolution CT of the thorax revealed diffuse thickening of the whole tracheal and bronchial wall, and bronchiectasis in the lower lobes.[ncbi.nlm.nih.gov]
Chest x‐rays showed hyperaeration and segmental atelectasis. High‐resolution CT of the thorax revealed diffuse thickening of the whole tracheal and bronchial wall, and bronchiectasis in the lower lobes.[doi.org]
We studied 15 articles on treatment of xanthoma disseminatum. Local treatment with cryotherapy, radiotherapy, surgery, and carbon dioxide lasers have been attempted with various results.[ncbi.nlm.nih.gov]
CNS involvement carries a poor prognosis in this otherwise benign condition.[ncbi.nlm.nih.gov]
What is the Prognosis of Xanthoma Disseminatum? (Outcomes/Resolutions) The prognosis of Xanthoma Disseminatum (XD) depends on the type of condition and the symptoms that manifest.[dovemed.com]
Prognosis often resistant to treatment Localization mucocutaneous ocular laryngeal pituitary central nervous system liver ( 16354260 ) See also systemic histiocytoses non-Langerhans cell histiocytoses dermal dendrocytes dendrocytic tumors (dendrocytic[humpath.com]
Even with this escalation of treatment, progressive cases of XD typically have a poor prognosis.[dermatologyadvisor.com]
Xanthoma disseminatum is a rare, benign, non-Langerhans' cell histiocytic disorder of unknown etiology.[ncbi.nlm.nih.gov]
Xanthoma Disseminatum: Case Report Abstract Xanthoma disseminatum is a rare, benign, non-Langerhans cell histiocytic disorder of unknown etiology.[adc.mef.hr]
Tumoral pathology xanthoma disseminatum Xanthoma disseminatum is a rare, usually self- healing dermatologic disease of unknown etiology . Involvement of other organs and tissues including bone marrow, bone, and brain may be seen rarely in children.[humpath.com]
XD could be differentiated from BCH on the basis of epidemiological, clinical and histopathological findings. One hypothesis could link such circumscribed localization to some regional (dis-)immune factors (10).[medicaljournals.se]
Definition / general Localized mass forming collection of lipid bearing histiocytes Terminology Also called xanthomatous polyp, xanthogranulomatous inflammation, xanthelasma Epidemiology Very rare in colon - stomach is most common gastrointestinal site[pathologyoutlines.com]
The pathogenesis of NLCH is not clear 1 ; however, there is some information about the epidemiology and clinical findings. First, XD usually starts before the age of 25 years in about 60% of patients 1 . Second, it is more common in males 1 .[synapse.koreamed.org]
Etiology Pathophysiology The etiology and pathogenesis of XD are unknown. Some authors have speculated that the association with paraproteinemia suggests an immunologic basis for this disease.[dermatologyadvisor.com]
Department of Molecular Medicine, IRCCS San Matteo Foundation, University of Pavia, Pavia, 2 Unit of Dermatology, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Via Pace 9, Milan, 3 Department of Oncology and Hematology, and 4 Department of Pathophysiology[medicaljournals.se]
Indeed, the different subtypes of NLH share largely common immune, histopathological and probably pathophysiological features, and their differential diagnosis is frequently based on some specific organ involvements.[karger.com]
Xanthomas associated with hyperlipidemia require treatment of the lipid disorder to reduce the xanthomas and prevent possible risks (such as atherosclerosis) (2).[empowher.com]
Although many conservative treatments are unsatisfactory, active intervention may still be warranted for the noninvoluting or disfiguring type for cosmetic reasons or to prevent permanent functional impairments. [1] :: Case Report A 10-year-old male child[jpgmonline.com]
A thorough workup is essential to identify the underlying condition in order to initiate early treatment and to prevent later complications.[austinpublishinggroup.com]
Treatment of eruptive xanthoma involves dietary restriction, exercise, and drug therapy to control the hyperlipidemia and the diabetes. 2 Early recognition and proper control of hypertriglyceridemia can prevent sequelae such as acute pancreatitis. 3[mdedge.com]