Presentation
To further investigate the genomic diversity among this group and to help characterize lineages of the plague organism that have no sequenced members, we present here the genomes of two isolates of the "classical" antiqua biovar, strains Antiqua and Nepal516 [ncbi.nlm.nih.gov]
Continent/Country/Region Distribution Last Reported Origin First Reported Invasive Reference Notes Asia China Present CAB ABSTRACTS Data Mining 2001 North America USA Present CAB ABSTRACTS Data Mining 2001 Distribution Maps Top of page You can pan and [cabi.org]
Entire Body System
- Camping
These Y. pestis mutants were more susceptible to the CAMPs cecropin A and polymyxin B, and produced lipid A lacking Ara4N modifications. [ncbi.nlm.nih.gov]
“Many San Franciscans lived in crowded temporary shelters and cottages in refugee camps. Accumulated garbage and debris created a congenial environment for rats, some of which carried bubonic plague.” [findingdulcinea.com]
DeWitte Institute of Applied Genetics, University of North Texas Health Science Center, 3500 Camp Bowie Boulevard, Fort Worth, Texas 76107, USA Sarah Schmedes Department of Anthropology and Population Research Institute, Pennsylvania State University, [doi.org]
Cardiovascular
- Thrombosis
Journal of Thrombosis and Haemostasis published by Wiley Periodicals, Inc. on behalf of International Society on Thrombosis and Haemostasis. [ncbi.nlm.nih.gov]
Psychiatrical
- Suggestibility
A differential host-specific type of binding to ECM proteins by YapV, YapK, and YapJ suggested that these proteins participate in broadening the host range of Y. pestis. [ncbi.nlm.nih.gov]
Neurologic
- Neglect
CONCLUSION: Most flea-borne infections are neglected diseases which should be monitored systematically in domestic rural and urban human populations to assess their epidemiological and clinical relevance. [ncbi.nlm.nih.gov]
Small, An Encapsulated Yersinia pseudotuberculosis Is a Highly Efficient Vaccine against Pneumonic Plague, PLoS Neglected Tropical Diseases, 6, 2, (e1528), (2012). [doi.org]
PLOS Neglected Tropical Diseases 9 ( 6 ) : e0003844 Riehm J, Vergnaud G, Kiefer D, Damdindorj T, Dashdavaa O, Khurelsukh T, Zöller L, Wölfel R, Fléche PL, Scholz H. 2012. Yersinia pestis lineages in Mongolia. [peerj.com]
Workup
Microbiology
- Staphylococcus Aureus
Methicillin-resistant Staphylococcus aureus survived on dry hospital mops up to 56 days ( 19 ). [doi.org]
- Legionella Pneumophila
Finally, we show that Rab1b knockdown also impacts the pH of the Legionella pneumophila containing vacuole, another pathogen that recruits Rab1b to its vacuole. [ncbi.nlm.nih.gov]
For example, Legionella pneumophila is resuscitated only in the presence of specific amoebae [40]. Similarly, the Rpf gene product of Micrococcus luteus is required by Mycobacterium tuberculosis to exit dormancy [41]. [journals.plos.org]
- Rickettsia Prowazekii
The human body louse is known as a vector for the transmission of three serious diseases-specifically, epidemic typhus, trench fever, and relapsing fever caused by Rickettsia prowazekii, Bartonella quintana, and Borrelia recurrentis, respectively-that [ncbi.nlm.nih.gov]
- Rickettsia Typhi
In Xenopsylla cheopis fleas collected from Cotonou (Benin), Rickettsia typhi was detected in 1% (2/199), and an uncultured Bartonella sp. was detected in 34.7% (69/199). [ncbi.nlm.nih.gov]
Treatment
[…] information 1 National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, State Key Laboratory for Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment [ncbi.nlm.nih.gov]
The NanoLogix Solution - Live-threat microorganism detection in 24 hours Without treatment, the mortality rate for Y. pestis is about 50-90 percent. However, the rate is cut to appoximately 1-15 percent with treatment. [nanologix.com]
Treatment of Yersinia Pestis Without treatment the fatality rate is high – more than 90%. With treatment this drops to between 5 and 20%. Rapid treatment with antibiotics such as streptomycin and tetracycline is the most common procedure. [brighthub.com]
Prognosis
[…] and fibrinolysin bacteria migrate to regional lymph nodes and survive intracellularly within macrophages F1 capsular antigen is antiphagocytic Prevention plague vaccine field workers in endemic areas laboratory personnel who work with Yersinia pestis Prognosis [step1.medbullets.com]
Etiology
Yersinia pestis, the etiologic agent of the disease plague, has been implicated in three historical pandemics. [ncbi.nlm.nih.gov]
Our findings confirm that Y. pestis was responsible for the Justinianic Plague, which should end the controversy regarding the etiology of this pandemic. [duo.uio.no]
Epidemiology
Our findings indicate wgMLST is a simplified, sensitive, and scalable tool for epidemiologic analysis of Y. pestis strains. Published by Elsevier Inc. KEYWORDS: Molecular epidemiology; Plague; Whole genome sequencing; Yersinia pestis; wgMLST [ncbi.nlm.nih.gov]
Pathophysiology
The fruit of our work has led to a better understanding of the pathophysiology of the disease in the insect and the identification of new Y. pestis genes required for the infection thanks to our development of an innovative technology (allowing the screening [pasteur-lille.fr]
Prevention
Author information 1 National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, State Key Laboratory for Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis [ncbi.nlm.nih.gov]