Patients normally present with symptoms similar to those of appendicitis, due to mesenteric adenitis. [ncbi.nlm.nih.gov]

• Goiter

  Extracts containing hTSHR were isolated from surgical thyroid tissue of patients with clinical and diagnostic signs of diffuse toxic goiter. [ncbi.nlm.nih.gov]

• Increased Susceptibility to Infections

  We propose that, because of defects in mucosal barrier function and immunological function, patients with Crohn's may have increased susceptibility to infection by Yersinia sp. [ncbi.nlm.nih.gov]

• Fever of Unknown Origin

  The patient had no history of immunosuppression and presented with a repeat case of haemarthrosis with a fever of unknown origin. Furthermore, he suffered from acute-on-chronic renal failure and non-ST segment elevation myocardial infarction. [ncbi.nlm.nih.gov]

• Sputum

  One strain of serotype O3 was isolated from the sputum of a patient with a fever and pneumonia in China. In Western countries, HPI (including an incomplete HPI) was detected in all serotype O1a strains and 84% of serotype O1b strains. [doi.org]

• Polydipsia

  Abstract A case concerning a young man presenting with polyuria and polydipsia which were preceded 1 month earlier by a febrile enteritis is reported. [ncbi.nlm.nih.gov]

• Recurrent Vomiting

  He had fever for 5 days after recurrent vomiting and diarrhea. Computed tomography scan was normal, but electroencephalogram (EEG) analyses showed generalized slow wave patterns. [ncbi.nlm.nih.gov]

• Aphthous Ulceration

  Colonoscopic examination revealed aphthous ulcers in the right colon, and mucosal biopsy culture grew Yersinia pseudotuberculosis. This case documents right colonic ulcers and bloody diarrhea with Yersinia pseudotuberculosis. [ncbi.nlm.nih.gov]

• Encephalopathy

  We report the case of a 28-month-old boy with encephalopathy and acute tubulointerstitial nephritis possibly associated with Yersinia pseudotuberculosis (Yp) infection. [ncbi.nlm.nih.gov]

• Pyuria

  The girl presented with remittent fever, vomiting and non-oliguric acute renal failure with sterile pyuria and tubular reabsorptive dysfunction. [ncbi.nlm.nih.gov]

• Abnormal Renal Function

  Ultrasound examination revealed that the kidneys were markedly enlarged with diffuse hyperechogenicity in the cortex when the abnormal renal function was present and were restored in size and echogenicity when the renal function normalised. [ncbi.nlm.nih.gov]

• Colonic Ulcer

  This case documents right colonic ulcers and bloody diarrhea with Yersinia pseudotuberculosis. [ncbi.nlm.nih.gov]

The Y. pseudotuberculosis septicaemia responded well to treatment with doxycycline orally, but the patient died 2 weeks later because of excessive bleeding from varicose veins of the oesophagus. [ncbi.nlm.nih.gov]

Infection usually becomes apparent 5–10 days after exposure and typically lasts 1–3 weeks without treatment. [wikidoc.org]

Prognosis Most pseudotuberculosis cases are either minimally symptomatic or self-limited. [emedicine.com]

Abstract Enteropathogenic Yersinia enterocolitica and Yersinia pseudotuberculosis are both etiological agents for intestinal infection known as yersiniosis, but their epidemiology and ecology bear many differences. [ncbi.nlm.nih.gov]

Y pseudotuberculosis has also been implicated in the etiology of some cases of Kawasaki disease. [6] Because of its 97% DNA homology with the agent that causes plague, Yersinia pestis, Y pseudotuberculosis is believed to have been the progenitor of the [emedicine.com]

Rarely, it has been associated with sepsis. [1] [2] [3] Etiology United States No specific pattern of Yersinia pseudotuberculosis infection has been reported. [statpearls.com]

The development of a fast and inexpensive typing system is necessary to facilitate epidemiological studies of Y. pseudotuberculosis infections. [ncbi.nlm.nih.gov]

[…] progenitor of the plague bacillus and is considered a model of bacterial evolution. [7] More optimistically, a specific strain of Y pseudotuberculosis, IP32953, has been modified into a potentially promising vaccine against bubonic and pneumonic plague. [8] Pathophysiology [emedicine.com]

Pathophysiology One usually acquires Yersinia pseudotuberculosis from the gastrointestinal (GI) tract after consumption of contaminated food. A large inoculum is usually required to produce disease. [statpearls.com]

The clinical pathophysiology of Y. pseudotuberculosis has many similarities to that of infections caused by Staphylococcus aureus and Streptococcus pyogenes, which are each known to produce a superantigen ( 38 ). [doi.org]

Author information 1 National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, State Key Laboratory for Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis [ncbi.nlm.nih.gov]