Presentation
Blood 2013 122:311; doi: A 52-year-old African-American woman with a history of allergic rhinitis and alcohol abuse presented with a presyncope. [bloodjournal.org]
Modifying the labeling to specify that the product contains zinc as an ingredient, if appropriate and consider replacing zinc with an ingredient that presents less health risks in situations of overuse. [fda.gov]
Hepcidin is a peptide hormone that is present in higher concentrations when body iron is replete [52]. [en.wikipedia.org]
Entire Body System
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Anemia
Overexposure to zinc can be toxic and lead to several conditions including neuropathy, anemia, paralysis, and bone issues. [atkinsandmarkoff.com]
Our impression was that sideroblastic anemia caused by copper deficiency induced by zinc lozenge use was a significant component of the severe anemia. [bloodjournal.org]
"Zinc abuse: an unsuspected cause of sideroblastic anemia". West J Med. 152 : 190–2. PMC 1002314. PMID 2400417. Fiske, D.N. (1994). [en.wikipedia.org]
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Pain
Many people do not even know the cream they are using contains zinc until they have already had to endure the painful consequences. [atkinsandmarkoff.com]
[…] is an essential trace metal with very low toxicity in humans. [1] [5] Signs and symptoms [ edit ] Following an oral intake of extremely high doses of zinc (where 300 mg Zn/d – 20 times the US RDA – is a "low intake" overdose [1] ), nausea, vomiting, pain [en.wikipedia.org]
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Fishing
For adult fish the temperatures are 27–29 C. A self-cleaning hatchery inlet screen and a spray jet for circular ponds are described. [publish.csiro.au]
The free zinc ion in solution is highly toxic to bacteria, plants, invertebrates, and even vertebrate fish. [2] [3] [4] Zinc is an essential trace metal with very low toxicity in humans. [1] [5] Signs and symptoms [ edit ] Following an oral intake of [en.wikipedia.org]
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Weakness
The symptoms of zinc poisoning include: Unexplained weakness Numbness Tingling in hands and feet Poor balance Lack of coordination Unexplained pain Weakness in the hands, arms or legs Burning sensation Feeling of wearing gloves or socks when the skin [atkinsandmarkoff.com]
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Dentist
Consider speaking to your dentist to see that your dentures fit properly. Dentures can become ill-fitting as a person's gums change over time. [fda.gov]
Respiratoric
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Rhinitis
Blood 2013 122:311; doi: A 52-year-old African-American woman with a history of allergic rhinitis and alcohol abuse presented with a presyncope. [bloodjournal.org]
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Cough
The patient admitted to self-treating her chronic cough with zinc lozenges for the last 4 months. Our impression was that sideroblastic anemia caused by copper deficiency induced by zinc lozenge use was a significant component of the severe anemia. [bloodjournal.org]
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Chronic Cough
The patient admitted to self-treating her chronic cough with zinc lozenges for the last 4 months. Our impression was that sideroblastic anemia caused by copper deficiency induced by zinc lozenge use was a significant component of the severe anemia. [bloodjournal.org]
Gastrointestinal
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Nausea
[2] [3] [4] Zinc is an essential trace metal with very low toxicity in humans. [1] [5] Signs and symptoms [ edit ] Following an oral intake of extremely high doses of zinc (where 300 mg Zn/d – 20 times the US RDA – is a "low intake" overdose [1] ), nausea [en.wikipedia.org]
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Diarrhea
[…] trace metal with very low toxicity in humans. [1] [5] Signs and symptoms [ edit ] Following an oral intake of extremely high doses of zinc (where 300 mg Zn/d – 20 times the US RDA – is a "low intake" overdose [1] ), nausea, vomiting, pain, cramps and diarrhea [en.wikipedia.org]
Psychiatrical
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Suggestibility
These findings suggest that zinc poisoning is an evolutionarily conserved process and might act in concert with other strategies to kill bacteria inside phagosomes. 2018. Published by The Company of Biologists Ltd [jcs.biologists.org]
Neurologic
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Ataxia
Zinc poisoning Pathology Type Toxin Cause(s) Ingestion of zinc, such as pennies or dental adhesive Symptoms Lethargy, ataxia, peripheral neuropathy. [house.fandom.com]
But in large quantities, it is extremely dangerous and can cause neuropathy, ataxia, lethargy, copper deficiency, anemia, paralysis, and bone marrow problems. A person who regularly uses a denture cream containing zinc may never experience problems. [atkinsandmarkoff.com]
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Lethargy
Zinc poisoning Pathology Type Toxin Cause(s) Ingestion of zinc, such as pennies or dental adhesive Symptoms Lethargy, ataxia, peripheral neuropathy. [house.fandom.com]
But in large quantities, it is extremely dangerous and can cause neuropathy, ataxia, lethargy, copper deficiency, anemia, paralysis, and bone marrow problems. A person who regularly uses a denture cream containing zinc may never experience problems. [atkinsandmarkoff.com]
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Tingling
The symptoms of zinc poisoning include: Unexplained weakness Numbness Tingling in hands and feet Poor balance Lack of coordination Unexplained pain Weakness in the hands, arms or legs Burning sensation Feeling of wearing gloves or socks when the skin [atkinsandmarkoff.com]
Stop using the denture adhesive and consult your physician if you experience symptoms such as numbness or tingling sensations in the extremities. [fda.gov]
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Peripheral Neuropathy
Zinc poisoning Pathology Type Toxin Cause(s) Ingestion of zinc, such as pennies or dental adhesive Symptoms Lethargy, ataxia, peripheral neuropathy. [house.fandom.com]
Unlike iron, the elimination of zinc is concentration-dependent. [13] Cross-reaction toxicity [ edit ] Supplemental zinc can prevent iron absorption, leading to iron deficiency and possible peripheral neuropathy, with loss of sensation in extremities. [en.wikipedia.org]
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Burning Sensation
The symptoms of zinc poisoning include: Unexplained weakness Numbness Tingling in hands and feet Poor balance Lack of coordination Unexplained pain Weakness in the hands, arms or legs Burning sensation Feeling of wearing gloves or socks when the skin [atkinsandmarkoff.com]
Workup
The workup was negative for hemolysis or bleeding. Her blood alcohol level was normal. B 12 and folate levels were normal. A peripheral smear showed dimorphic red blood cells with Pappenheimer bodies (panel A). [bloodjournal.org]
Treatment
Mortality Rate Low Treatments Physical removal of source Show Information Appearances Selfish [Source] Zinc poisoning is caused by the accidental or deliberate ingestion of zinc compounds. [house.fandom.com]
Treatment [ edit ] None. See also [ edit ] Zinc deficiency References [ edit ] a b c d e f Fosmire GJ (February 1990). "Zinc toxicity". Am. J. Clin. Nutr. 51 (2): 225–7. PMID 2407097. Rout, Gyana Ranjan; Das, Premananda (1 January 2003). [en.wikipedia.org]
Prevention
Higher concentrations of hepcidin prevent ingested iron from entering the bloodstream by trapping iron in enterocytes which are naturally shed every two days [112], thereby preventing body iron from escalating to dangerous levels. [en.wikipedia.org]
To help address the potential risk that overuse of zinc-containing denture adhesives may pose, the FDA asked makers of zinc-containing denture adhesives to consider: Including directions that will prevent overuse if zinc is an ingredient. [fda.gov]