Blood 2013 122:311; doi: https://doi.org/10.1182/blood-2012-12-469239 A 52-year-old African-American woman with a history of allergic rhinitis and alcohol abuse presented with a presyncope. [bloodjournal.org]

The case looks much more serious when a high mineral content is present in the body for a long time. [olimpsport.com]

Modifying the labeling to specify that the product contains zinc as an ingredient, if appropriate and consider replacing zinc with an ingredient that presents less health risks in situations of overuse. [fda.gov]

Hepcidin is a peptide hormone that is present in higher concentrations when body iron is replete [52]. [en.wikipedia.org]

• Anemia

  Overexposure to zinc can be toxic and lead to several conditions including neuropathy, anemia, paralysis, and bone issues. [atkinsandmarkoff.com]

  Our impression was that sideroblastic anemia caused by copper deficiency induced by zinc lozenge use was a significant component of the severe anemia. [bloodjournal.org]

  "Zinc abuse: an unsuspected cause of sideroblastic anemia". West J Med. 152 : 190–2. PMC 1002314. PMID 2400417. ^ Fiske, D.N. (1994). [en.wikipedia.org]

  Other and equally serious effects of a zinc overdose include: reduction of an optimal LDL cholesterol concentration increased risk of anemia (especially of kidneys and liver), a clear decline and deterioration of the body's immune response. [olimpsport.com]

• Pain

  Many people do not even know the cream they are using contains zinc until they have already had to endure the painful consequences. [atkinsandmarkoff.com]

  […] is an essential trace metal with very low toxicity in humans. [1] [5] Signs and symptoms [ edit ] Following an oral intake of extremely high doses of zinc (where 300 mg Zn/d – 20 times the US RDA – is a "low intake" overdose [1] ), nausea, vomiting, pain [en.wikipedia.org]

• Falling

  Chelation therapy promoted dramatic clinical improvement, and a fall in blood zinc levels. Full Text [jamanetwork.com]

• Weakness

  The symptoms of zinc poisoning include: Unexplained weakness Numbness Tingling in hands and feet Poor balance Lack of coordination Unexplained pain Weakness in the hands, arms or legs Burning sensation Feeling of wearing gloves or socks when the skin [atkinsandmarkoff.com]

• Nausea

  [2] [3] [4] Zinc is an essential trace metal with very low toxicity in humans. [1] [5] Signs and symptoms [ edit ] Following an oral intake of extremely high doses of zinc (where 300 mg Zn/d – 20 times the US RDA – is a "low intake" overdose [1] ), nausea [en.wikipedia.org]

• Diarrhea

  […] trace metal with very low toxicity in humans. [1] [5] Signs and symptoms [ edit ] Following an oral intake of extremely high doses of zinc (where 300 mg Zn/d – 20 times the US RDA – is a "low intake" overdose [1] ), nausea, vomiting, pain, cramps and diarrhea [en.wikipedia.org]

• Tingling

  The symptoms of zinc poisoning include: Unexplained weakness Numbness Tingling in hands and feet Poor balance Lack of coordination Unexplained pain Weakness in the hands, arms or legs Burning sensation Feeling of wearing gloves or socks when the skin [atkinsandmarkoff.com]

  Stop using the denture adhesive and consult your physician if you experience symptoms such as numbness or tingling sensations in the extremities. [fda.gov]

The workup was negative for hemolysis or bleeding. Her blood alcohol level was normal. B 12 and folate levels were normal. A peripheral smear showed dimorphic red blood cells with Pappenheimer bodies (panel A). [bloodjournal.org]

Mortality Rate Low Treatments Physical removal of source Show Information Appearances Selfish [Source] Zinc poisoning is caused by the accidental or deliberate ingestion of zinc compounds. [house.fandom.com]

PMID: 24264023 Brain-Delivery of Zinc-Ions as Potential Treatment for Neurological Diseases: Mini Review. Grabrucker AM, Rowan M, Garner CC. Grabrucker AM, et al. Drug Deliv Lett. 2011 Sep;1(1):13-23. doi: 10.2174/2210303111101010013. [pubmed.ncbi.nlm.nih.gov]

Treatment [ edit ] None. See also [ edit ] Zinc deficiency References [ edit ] ^ a b c d e f Fosmire GJ (February 1990). "Zinc toxicity". Am. J. Clin. Nutr. 51 (2): 225–7. PMID 2407097. ^ Rout, Gyana Ranjan; Das, Premananda (1 January 2003). [en.wikipedia.org]

Higher concentrations of hepcidin prevent ingested iron from entering the bloodstream by trapping iron in enterocytes which are naturally shed every two days [112], thereby preventing body iron from escalating to dangerous levels. [en.wikipedia.org]

To help address the potential risk that overuse of zinc-containing denture adhesives may pose, the FDA asked makers of zinc-containing denture adhesives to consider: Including directions that will prevent overuse if zinc is an ingredient. [fda.gov]