When cilia go bad: cilia defects and ciliopathies.

2007: TBenzing; MFliegauf; HOmran;

Nat Rev Mol Cell Biol.2007;8(11):880-93.

NLM PMID: 17955020

Article abstract

Defects in the function of cellular organelles such as peroxisomes, lysosomes and mitochondria are well-known causes of human diseases. Recently, another organelle has also been added to this list. Cilia--tiny hair-like organelles attached to the cell surface--are located on almost all polarized cell types of the human body and have been adapted as versatile tools for various cellular functions, explaining why cilia-related disorders can affect many organ systems. Several molecular mechanisms involved in cilia-related disorders have been identified that affect the structure and function of distinct cilia types.

Research Topics
• Diseases
   Ciliary Motility Disorders
   Cysts

Title and Abstract from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
Data mined from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

Last MEDLINE®/PubMed® update: 1st of December 2015