Top 20 of Adenoma

Article title # Publications/# Citations

Lessons from hereditary colorectal cancer.

1996: KWKinzler; BVogelstein;

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Genetic alterations during colorectal-tumor development.

1988: JLBos; ERFearon; SRHamilton; SEKern; MLeppert; YNakamura; ACPreisinger; AMSmits; BVogelstein; RWhite;

720

Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells.

2005: HBegthel; HClevers; MCozijnsen; FRadtke; ORiccio; SRobine; Mvan den Born; JHvan Es; ... MEvan Gijn; MVooijs; DJWinton;

323

Randomised controlled trial of faecal-occult-blood screening for colorectal cancer.

1996: SSAmar; TWBalfour; JOChamberlain; JDHardcastle; PDJames; CMMangham; SMMoss; MHRobinson;

322

Crypt stem cells as the cells-of-origin of intestinal cancer.

2008: NBarker; HBegthel; ARClarke; HClevers; EDanenberg; RARidgway; OJSansom; Mvan de Wetering; Mvan den Born; JHvan Es;

310

Randomised study of screening for colorectal cancer with faecal-occult-blood test.

1996: CFenger; ODJørgensen; OKronborg; JOlsen; OSøndergaard;

292

A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice.

1996: VBroudy; CECarow; MLFero; EFirpo; KKaushansky; RMPerlmutter; KPolyak; PPorter; ... MRivkin; JMRoberts; MTasch; LHTsai;

290

Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas.

1994: RJCoffey; RNDuBois; CEEberhart; SFerrenbach; FMGiardiello; ARadhika;

280

A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse.

1990: WFDove; ARMoser; HCPitot;

276

APC mutations occur early during colorectal tumorigenesis.

1992: YBeazer-Barclay; TMBryan; SRHamilton; KWKinzler; SMPowell; SNThibodeau; BVogelstein; NZilz;

276

Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network.

2008: LAAarden; CJDesmet; SDouma; TKuilman; CMichaloglou; WJMooi; DSPeeper; Rvan Doorn; LCVredeveld;

257

Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors.

2002: JBehrens; WBirchmeier; HClevers; BJerchow; UKarsten; BLustig; TPietsch; MSachs; ... PMSchlag; Mvan de Wetering; SWeiler;

247

Prevalence of ras gene mutations in human colorectal cancers.

1987 May 28-Jun 3: JLBos; ERFearon; SRHamilton; JHvan Boom; AJvan der Eb; MVerlaan-de Vries; BVogelstein;

247

Telomere reduction in human colorectal carcinoma and with ageing.

1990: RCAllshire; MDempster; MGDunlop; DKGreen; NDHastie; AMThompson;

243

A randomized trial of aspirin to prevent colorectal adenomas.

2003: DAhnen; JIAllen; JABaron; MBeach; GJBeck; JHBond; RBresalier; CABurke; ... TByers; TRChurch; BFCole; ERGreenberg; RWHaile; JSMandel; NMarcon; GMcKeown-Eyssen; LAMott; LPearson; RRothstein; FSaibil; RSSandler; DCSnover; RWSummers; RUVan Stolk;

200

Computed tomographic virtual colonoscopy to screen for colorectal neoplasia in asymptomatic adults.

2003: JAButler; JRChoi; HAHildebrandt; IHwang; PAMysliwiec; PANugent; PJPickhardt; MLPuckett; WRSchindler; RKWong;

199

Celecoxib for the prevention of sporadic colorectal adenomas.

2006: APC Study Investigators; WFAnderson; DBagheri; MMBertagnolli; FBoisserie; JBurn; DCChung; DCorle; ... TDewar; CJEagle; TRFoley; GBGordon; ETHawk; TMHess; NHoffman; KKim; FMacrae; REPruitt; MRedston; RBRosenstein; JRSaltzman; BSalzberg; SDSolomon; TSylwestrowicz; JTang; JLViner; JWittes; GMWoloj; AGZauber;

194

Use of colonoscopy to screen asymptomatic adults for colorectal cancer. Veterans Affairs Cooperative Study Group 380.

2000: DJAhnen; JHBond; GChejfec; HGarewal; DALieberman; DGWeiss;

186

A novel cyclin encoded by a bcl1-linked candidate oncogene.

1991: AArnold; TBloom; HJüppner; HGKim; HMKronenberg; TMotokura; JVRuderman;

179

YAP1 increases organ size and expands undifferentiated progenitor cells.

2007: GWBell; TRBrummelkamp; FDCamargo; DFu; SGokhale; RJaenisch; JBJohnnidis;

173