Top 20 of Central Nervous System Diseases

Article title # Publications/# Citations

Microglia: a sensor for pathological events in the CNS.

1996: GWKreutzberg;

465

Function and regulation of CREB family transcription factors in the nervous system.

2002: DDGinty; BELonze;

337

Astrocytes: biology and pathology.

2009: MVSofroniew; HVVinters;

259

Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis.

1996: MBinder; MMarín-Padilla; AHSharpe; NASpeck; TStacy; QWang;

217

Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders.

2009: AChristopoulos; PJConn; CWLindsley;

183

Local self-renewal can sustain CNS microglia maintenance and function throughout adult life.

2007: BAjami; JLBennett; CKrieger; FMRossi; WTetzlaff;

169

Therapeutic application of histone deacetylase inhibitors for central nervous system disorders.

2008: AGKazantsev; LMThompson;

145

Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells.

2007: BCiric; MEl-Behi; DCFitzgerald; ZFonseca-Kelly; BGran; HLi; ARostami; CJSaris; SYu; GXZhang;

144

The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease.

2002: MBravo; EMHur; DJMitchell; JCPatarroyo; JLRadosevich; PJRuiz; RASobel; LSteinman; ... OStuve; SYoussef; SSZamvil;

134

Stem cells in the central nervous system.

1997: RMcKay;

133

Microglia as mediators of inflammatory and degenerative diseases.

1999: GBaltuch; FGonzález-Scarano;

129

Neuronal migration, with special reference to developing human brain: a review.

1973: PRakic; RLSidman;

124

Targeting the endocannabinoid system: to enhance or reduce?

2008: VDi Marzo;

124

The role of inflammation in CNS injury and disease.

2006: RMGibson; SMLucas; NJRothwell;

123

A FAMILIAL DISORDER OF URIC ACID METABOLISM AND CENTRAL NERVOUS SYSTEM FUNCTION.

1964: MLesch; WLNyhan;

120

Glial fibrillary acidic protein: GFAP-thirty-one years (1969-2000).

2000: LFEng; RSGhirnikar; YLLee;

118

CNS injury, glial scars, and inflammation: Inhibitory extracellular matrices and regeneration failure.

2007: MTFitch; JSilver;

117

Age-dependent emergence and progression of a tauopathy in transgenic mice overexpressing the shortest human tau isoform.

1999: MHong; TIshihara; MKLee; VMLee; YNakagawa; JQTrojanowski; BZhang;

111

An apparently new enterovirus isolated from patients with disease of the central nervous system.

1974: HHHo; EHLennette; NJSchmidt;

106

Cholesterol metabolism in the brain.

2001: JMDietschy; SDTurley;

106