Top 20 of Chromosome Deletion

Article title # Publications/# Citations

A genetic model for colorectal tumorigenesis.

1990: ERFearon; BVogelstein;

1236

SV40-transformed simian cells support the replication of early SV40 mutants.

1981: YGluzman;

869

Sequence logos: a new way to display consensus sequences.

1990: TDSchneider; RMStephens;

821

Genetic alterations during colorectal-tumor development.

1988: JLBos; ERFearon; SRHamilton; SEKern; MLeppert; YNakamura; ACPreisinger; AMSmits; BVogelstein; RWhite;

720

A short amino acid sequence able to specify nuclear location.

1984: DKalderon; WDRichardson; BLRoberts; AESmith;

601

Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus.

1983: DBaltimore; RMann; RCMulligan;

547

Identification of the cystic fibrosis gene: genetic analysis.

1989: JABuchanan; MBuchwald; AChakravarti; TKCox; BKerem; DMarkiewicz; JMRommens; LCTsui;

547

Construction of a genetic linkage map in man using restriction fragment length polymorphisms.

1980: DBotstein; RWDavis; MSkolnick; RLWhite;

522

Tumor spectrum analysis in p53-mutant mice.

1994: RTBronson; SHalachmi; TJacks; LRemington; EMSchmitt; RAWeinberg; BOWilliams;

500

Importance of the nef gene for maintenance of high virus loads and for development of AIDS.

1991: MDDaniel; RCDesrosiers; HWKestler; KMori; DLPanicali; DJRingler; PKSehgal;

499

Construction of an eae deletion mutant of enteropathogenic Escherichia coli by using a positive-selection suicide vector.

1991: MSDonnenberg; JBKaper;

459

Sequences that regulate the divergent GAL1-GAL10 promoter in Saccharomyces cerevisiae.

1984: RWDavis; MJohnston;

416

Rare chromosomal deletions and duplications increase risk of schizophrenia.

2008: International Schizophrenia Consortium;

383

A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma.

1986 Oct 16-22: DMAlbert; RBernards; TPDryja; SHFriend; JMRapaport; SRogelj; RAWeinberg;

380

Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis.

1994: WPBennett; MSGreenblatt; CCHarris; MHollstein;

379

Association between microdeletion and microduplication at 16p11.2 and autism.

2008: Autism Consortium; DAltshuler; DEArking; AChakravarti; MJDaly; MAFerreira; RFossdal; TGreen; ... JFGusella; JMKorn; DTMiller; OSPlatt; DMRuderfer; ESaemundsen; SLSantangelo; YShen; PSklar; HStefansson; KStefansson; RETanzi; CAWalsh; LAWeiss; BLWu;

368

Spliced early mRNAs of simian virus 40.

1978: AJBerk; PASharp;

362

Redesign of retrovirus packaging cell lines to avoid recombination leading to helper virus production.

1986: CButtimore; ADMiller;

356

Identification and characterization of the familial adenomatous polyposis coli gene.

1991: HAlbertsen; MCarlson; LGelbert; JGroden; GJoslyn; MRobertson; WSamowitz; LSpirio; JStevens; AThliveris;

350

A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus.

1985: MBoshart; KDorsch-Häsler; BFleckenstein; GJahn; WSchaffner; FWeber;

345