Top 20 of Colonic Neoplasms

Article title # Publications/# Citations

ras oncogenes in human cancer: a review.

1989: JLBos;

741

Genetic alterations during colorectal-tumor development.

1988: JLBos; ERFearon; SRHamilton; SEKern; MLeppert; YNakamura; ACPreisinger; AMSmits; BVogelstein; RWhite;

720

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC.

1997: NBarker; HClevers; KWKinzler; VKořínek; PJMorin; ABSparks; BVogelstein;

692

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells.

1999: FMcCormick; OTetsu;

692

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma.

1997: NBarker; HClevers; Rde Weger; KWKinzler; VKořínek; PJMorin; Dvan Wichen; BVogelstein;

689

A human colon cancer cell capable of initiating tumour growth in immunodeficient mice.

2006: JEDick; SGallinger; CAO'Brien; APollett;

624

Identification and expansion of human colon-cancer-initiating cells.

2006: MBiffoni; RDe Maria; DGLombardi; CPeschle; EPilozzi; LRicci-Vitiani; MTodaro;

613

Normalization of real-time quantitative reverse transcription-PCR data: a model-based variance estimation approach to identify genes suited for normalization, applied to bladder and colon cancer data sets.

2004: CLAndersen; JLJensen; TFØrntoft;

546

New colorimetric cytotoxicity assay for anticancer-drug screening.

1990: HBokesch; MRBoyd; SKenney; JMcMahon; AMonks; DScudiero; PSkehan; RStoreng; DVistica; JTWarren;

523

Comprehensive molecular characterization of human colon and rectal cancer.

2012: Cancer Genome Atlas Network;

510

IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer.

2004: LEckmann; LJEgan; FRGreten; TFGreten; MFKagnoff; MKarin; ZWLi; JMPark;

453

The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores.

2009: HCui; APFeinberg; KGabo; RAIrizarry; HJi; CLadd-Acosta; CMontano; POnyango; ... JBPotash; MRongione; SSabunciyan; MWebster; BWen; ZWu;

442

Design of the Women's Health Initiative clinical trial and observational study. The Women's Health Initiative Study Group.

1998:

423

The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer.

1993: NGCopeland; RFishel; JGarber; NAJenkins; MKane; RKolodner; MKLescoe; MRRao;

392

The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway.

1999: CAlbanese; ABen-Ze'ev; MD'Amico; RPestell; MShtutman; ISimcha; JZhurinsky;

389

Microsatellite instability in cancer of the proximal colon.

1993: GBren; DSchaid; SNThibodeau;

380

Suppression of human colorectal carcinoma cell growth by wild-type p53.

1990: SJBaker; ERFearon; SMarkowitz; BVogelstein; JKWillson;

360

Clues to the pathogenesis of familial colorectal cancer.

1993: LAAaltonen; SRHamilton; HJärvinen; JJen; FSLeach; JPMecklin; PPeltomäki; SMPowell; LPylkkänen; PSistonen;

359

Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy.

2007: SAmigorena; FAndré; LApetoh; FJBarrat; JBourhis; AChompret; FClavel-Chapelon; ACriollo; ... SDelaloge; FGhiringhelli; VJoulin; GKroemer; FLevi; RLidereau; MCMaiuri; GMignot; JPMira; CNogues; MObeid; COrtiz; BRyffel; PSaftig; PSaulnier; ATesnière; TTursz; EUllrich; HYang; LZitvogel;

347

Prevention of colorectal cancer by colonoscopic polypectomy. The National Polyp Study Workgroup.

1993: JHBond; LSGottlieb; MNHo; MJO'Brien; JFPanish; MSchapiro; SSSternberg; JDWaye; SJWinawer; AGZauber;

346