Top 20 of Diabetes Mellitus, Type 2

Article title # Publications/# Citations

Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man.

1985: JPHosker; DRMatthews; BANaylor; ASRudenski; DFTreacher; RCTurner;

2453

Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin.

2002: Diabetes Prevention Program Research Group; EBarrett-Connor; SEFowler; RFHamman; WCKnowler; JMLachin; DMNathan; EAWalker;

1696

Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group.

1998:

1580

Global prevalence of diabetes: estimates for the year 2000 and projections for 2030.

2004: AGreen; HKing; GRoglic; RSicree; SWild;

1195

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes.

2003: DAltshuler; ECarlsson; MJDaly; KFEriksson; TRGolub; LCGroop; JNHirschhorn; NHoustis; ... ESLander; ELaurila; JLehar; CMLindgren; JPMesirov; VKMootha; NPatterson; PPuigserver; MRidderstråle; SSihag; BSpiegelman; ASubramanian; PTamayo;

1073

Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement.

2005: American Heart Association; National Heart, Lung, and Blood Institute; JICleeman; FCosta; SRDaniels; KADonato; RHEckel; BAFranklin; ... DJGordon; SMGrundy; RMKrauss; PJSavage; SCSmith; JASpertus;

959

Inflammation and metabolic disorders.

2006: GSHotamisligil;

951

Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance.

2001: Finnish Diabetes Prevention Study Group; JGEriksson; HHämäläinen; PIlanne-Parikka; SKeinänen-Kiukaanniemi; MLaakso; JLindström; ALouheranta; ... MRastas; VSalminen; JTuomilehto; MUusitupa; TTValle;

859

The phosphoinositide 3-kinase pathway.

2002: LCCantley;

829

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.

2007: Diabetes Genetics Initiative of Broad Institute of Harvard and MIT, Lund University, and Novartis Institutes of BioMedical Research; PAlmgren; DAltshuler; KArdlie; RBarry; KBengtsson Boström; ABerglund; BBlumenstiel; ... WBrodeur; NPBurtt; JCamarata; JCarlson; HChen; NChia; GWChirn; MJDaly; PIde Bakker; MDeFelice; MFava; JCFlorez; SBGabriel; DGage; CGates; LGianniny; JGibbons; LGroop; CGuiducci; RHackett; LHall; BHandsaker; CHealy; JNHirschhorn; JHolmkvist; TEHughes; BIsomaa; SKathiresan; ELaurila; GLettre; ULindblad; HNLyon; VLyssenko; QMa; OMelander; JMeyer; CNewton-Cheh; KNguyen; PNilsson; MNizzari; MOrho-Melander; HParikh; MParkin; SPurcell; LRåstam; DRichardson; DRicke; JJRoix; RSaxena; MSjögren; CSougnez; EKSpeliotes; MSterner; ASurti; MSvensson; MSvensson; MRTaskinen; RTewhey; TTuomi; BFVoight;

815

Banting lecture 1988. Role of insulin resistance in human disease.

1988: GMReaven;

803

A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.

2007: GRAbecasis; CWBark; MWBarnhart; RNBergman; MBoehnke; LLBonnycastle; TABuchanan; PSChines; ... FSCollins; KNConneely; CJDing; KFDoheny; WLDuren; MRErdos; JLGoldstein; KNHetrick; THu; AUJackson; LKinnunen; XYLi; YLi; KLMohlke; NNarisu; LProkunina-Olsson; RPruim; EWPugh; NLRiebow; JSaramies; LJScott; AGSprau; HMStringham; AJSwift; MTong; JTuomilehto; TTValle; RMWatanabe; LWatkins; PPWhite; CJWiller; FXiang; RXiao;

772

Effects of intensive glucose lowering in type 2 diabetes.

2008: Action to Control Cardiovascular Risk in Diabetes Study Group; JTBigger; JBBuse; RPByington; WCCushman; WTFriedewald; SGenuth; HCGerstein; ... DCGoff; RHGrimm; FIsmail-Beigi; MEMiller; JLProbstfield; DGSimons-Morton;

755

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity.

2007: JCBarrett; IBarroso; YBen-Shlomo; AJBennett; LRCardon; ASDoney; SEbrahim; SEllard; ... KSElliott; LFerrucci; TMFrayling; RMFreathy; CJGroves; LWHarries; ATHattersley; GAHitman; MRJarvelin; FKarpe; BKnight; HLango; DALawlor; CMLindgren; RJLoos; MIMcCarthy; DMelzer; ADMorris; ARNess; KROwen; CNPalmer; AMPatch; JRPerry; NWRayner; SMRing; BShields; GDSmith; USovio; NJTimpson; MWalker; NJWareham; MNWeedon; EZeggini;

751

A genome-wide association study identifies novel risk loci for type 2 diabetes.

2007: DJBalding; BBalkau; ABélisle; PBoutin; GCharpentier; CDina; PFroguel; SHadjadj; ... BHeude; TJHudson; DMeyre; AMontpetit; CPolychronakos; BIPosner; MPrentki; AVPshezhetsky; GRocheleau; JRung; DSerre; LShen; RSladek; DVincent;

655

Role of AMP-activated protein kinase in mechanism of metformin action.

2001: YChen; TDoebber; JFenyk-Melody; NFujii; LJGoodyear; MFHirshman; YLi; DEMoller; ... NMusi; RMyers; XShen; JVentre; MWu; GZhou;

637

Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.

2007: Wellcome Trust Case Control Consortium (WTCCC); JCBarrett; LRCardon; ASDoney; SEllard; KSElliott; TMFrayling; RMFreathy; ... CJGroves; LWHarries; ATHattersley; GAHitman; BKnight; HLango; CMLindgren; JLMarchini; MIMcCarthy; ADMorris; APMorris; KROwen; JRPerry; NWRayner; BShields; NJTimpson; MWalker; MNWeedon; EZeggini;

630

Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes.

2008: ADVANCE Collaborative group; LBillot; SBompoint; JChalmers; MCooper; BEde Galan; PGlasziou; DGrobbee; ... PHamet; SHarrap; SHeller; RJoshi; LLiu; SMacMahon; GMancia; MMarre; CEMogensen; BNeal; CPan; APatel; NPoulter; ARodgers; FTravert; BWilliams; MWoodward;

617

Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes.

2004: QCao; LHGlimcher; CGorgun; GSHotamisligil; NNIwakoshi; AHLee; UOzcan; EOzdelen; GTuncman; EYilmaz;

579

Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study.

2000: AIAdler; CACull; DHadden; RRHolman; SEManley; DRMatthews; HANeil; IMStratton; RCTurner;

578