Top 20 of Disease

Article title # Publications/# Citations

APACHE II: a severity of disease classification system.

1985: EADraper; WAKnaus; DPWagner; JEZimmerman;

1166

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits.

2009: FSCollins; LAHindorff; HAJunkins; TAManolio; JPMehta; EMRamos; PSethupathy;

1019

Autophagy in the pathogenesis of disease.

2008: GKroemer; BLevine;

932

The Wnt signaling pathway in development and disease.

2004: CYLogan; RNusse;

922

Angiogenesis in cancer and other diseases.

2000: PCarmeliet; RKJain;

853

Antimicrobial peptides of multicellular organisms.

2002: MZasloff;

775

KEGG for linking genomes to life and the environment.

2007: MAraki; SGoto; MHattori; MHirakawa; MItoh; MKanehisa; TKatayama; SKawashima; ... SOkuda; TTokimatsu; YYamanishi;

755

Free radicals in the physiological control of cell function.

2002: WDröge;

730

Apoptosis in the pathogenesis and treatment of disease.

1995: CBThompson;

651

KEGG for integration and interpretation of large-scale molecular data sets.

2011: MFurumichi; SGoto; MKanehisa; YSato; MTanabe;

632

Nitric oxide and peroxynitrite in health and disease.

2007: JSBeckman; LLiaudet; PPacher;

624

Initial sequence of the chimpanzee genome and comparison with the human genome.

2005: Chimpanzee Sequencing and Analysis Consortium;

585

Wnt/beta-catenin signaling: components, mechanisms, and diseases.

2009: XHe; BTMacDonald; KTamai;

565

The DNA-damage response in human biology and disease.

2009: JBartek; SPJackson;

516

From inflammation to sickness and depression: when the immune system subjugates the brain.

2008: RDantzer; GGFreund; RWJohnson; KWKelley; JCO'Connor;

513

The pathophysiology of mitochondrial cell death.

2004: DRGreen; GKroemer;

495

The human disease network.

2007: ALBarabási; BChilds; MECusick; KIGoh; DValle; MVidal;

475

Coding algorithms for defining comorbidities in ICD-9-CM and ICD-10 administrative data.

2005: CABeck; BBurnand; TEFeasby; AFong; WAGhali; PHalfon; JCLuthi; HQuan; LDSaunders; VSundararajan;

446

Store-operated calcium channels.

2005: ABParekh; JWPutney;

427

The UCSC Genome Browser database: update 2011.

2010: GPBarber; HClawson; MSCline; ACoelho; MDiekhans; TRDreszer; PAFujita; BMGiardine; ... MGoldman; RAHarte; DHaussler; JHillman-Jackson; ASHinrichs; FHsu; DKarolchik; WJKent; VKirkup; RMKuhn; KLearned; CHLi; LRMeyer; APohl; BJRaney; BRhead; KRRosenbloom; KESmith; ASZweig;

427