Top 20 of Encephalomyelitis, Autoimmune, Experimental

Article title # Publications/# Citations

Interleukin-10 and the interleukin-10 receptor.

2001: RLCoffman; Rde Waal Malefyt; KWMoore; AO'Garra;

952

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation.

2005: BBasham; WMBlumenschein; YChen; DJCua; RAKastelein; CLLangrish; JMattson; TMcclanahan; JDSedgwick;

770

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain.

2003: YChen; TChurakova; DJCua; DGorman; BJoyce; RAKastelein; SKwan; SALira; ... LLucian; CAMurphy; JDSedgwick; BSeymour; JSherlock; WTo; MWiekowski; SZurawski;

568

IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells.

2007: AAwasthi; EBettelli; WGao; AJäger; TKorn; VKKuchroo; MOukka; TBStrom;

481

IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis.

2006: HIshigame; YIwakura; SKakuta; YKomiyama; TMatsuki; SNakae; ANambu; KSudo;

340

T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma.

2007: AAkimzhanov; YChung; CDong; AMJetten; HSKang; LMa; RNurieva; ADPanopoulos; ... BPPappu; KSSchluns; BShah; QTian; SSWatowich; XOYang;

329

Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis.

1994: YChen; DAHafler; JInobe; VKKuchroo; HLWeiner;

278

Molecular antagonism and plasticity of regulatory and inflammatory T cell programs.

2008: SHChang; YChung; CDong; XHFeng; AMJetten; HSKang; GJMartinez; RNurieva; ... BPPappu; KSSchluns; BShah; SSWatowich; XOYang;

262

The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins.

2008: JBuer; LDumoutier; KHirota; JCRenauld; BStockinger; MVeldhoen; AMWestendorf;

262

Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor.

2008: ASBasso; EBettelli; MCaccamo; MFFarez; AHIglesias; TKorn; MOukka; FJQuintana; HLWeiner;

260

Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis.

2002: JAllard; AAustin; ABrendolan; BCannella; SJGalli; HGarren; RHeller; GHermans; ... NKaminski; PKlonowski; NLad; ALanger-Gould; CLock; JROksenberg; RPedotti; CSRaine; ESchadt; LSteinman; SStrober;

248

Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity.

2009: CFBrereton; SJLalor; ECLavelle; KHMills; CESutton; CMSweeney;

247

A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis.

2006: CBrereton; BKeogh; ECLavelle; KHMills; CSutton;

227

B cells regulate autoimmunity by provision of IL-10.

2002: SMAnderton; SFillatreau; DGray; MJMcGeachy; CHSweenie;

227

B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy.

1995: JABrown; MPDas; LHGlimcher; VKKuchroo; NNabavi; AMRanger; RASobel; HLWeiner; SSZamvil;

225

Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin.

1992: CCannon; LCFritz; NKarin; FSanchez-Madrid; LSteinman; TAYednock;

216

Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation.

2007: AAwasthi; BTBäckström; EBettelli; WGao; TKorn; VKKuchroo; MOukka; TRPetersen; ... JReddy; RASobel; TBStrom; KWWucherpfennig;

206

Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells.

2006: MBatten; DMDanilenko; FJde Sauvage; NGhilardi; NMKljavin; JLee; JLi; SLucas; SYi;

203

The immune modulator FTY720 targets sphingosine 1-phosphate receptors.

2002: RAlbert; TBaumruker; VBrinkmann; CBruns; SCottens; MDDavis; CAFoster; CEHeise; ... PHiestand; RHof; KRLynch; EPrieschl; MZollinger;

202

Mice with a disrupted IFN-gamma gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE).

1996: SBrocke; DDalton; CDinisco; CGFathman; IAFerber; WRidgway; LSteinman; CTaylor-Edwards;

199