Top 20 of Glioblastoma

Article title # Publications/# Citations

Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.

2005: European Organisation for Research and Treatment of Cancer Brain Tumor and Radiotherapy Groups; National Cancer Institute of Canada Clinical Trials Group; AAllgeier; KBelanger; UBogdahn; AABrandes; JGCairncross; JCurschmann; ... EEisenhauer; BFisher; TGorlia; RCJanzer; DLacombe; SKLudwin; CMarosi; WPMason; ROMirimanoff; RStupp; MJTaphoorn; MJvan den Bent; MWeller;

1515

Comprehensive genomic characterization defines human glioblastoma genes and core pathways.

2008: Cancer Genome Atlas Research Network;

1330

An integrated genomic analysis of human glioblastoma multiforme.

2008: PAngenendt; DDBigner; DABusam; HCarter; LADiaz; GLGallia; JHartigan; SJones; ... RKarchin; SKeir; KWKinzler; RJLeary; JCLin; PMankoo; SKMarie; RMcLendon; TNikolskaya; YNikolsky; AOlivi; NPapadopoulos; GParmigiani; DWParsons; BARasheed; GJRiggins; SMShinjo; IMSiu; DRSmith; RLStrausberg; HTekleab; VEVelculescu; BVogelstein; HYan; XZhang;

959

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response.

2006: SBao; DDBigner; MWDewhirst; YHao; ABHjelmeland; REMcLendon; JNRich; QShi; QWu;

813

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer.

1997: SHBigner; SBose; BCGiovanella; HHibshoosh; MIttmann; JLi; DLiaw; RMcCombie; ... CMiliaresis; RParsons; KPodsypanina; JPuc; LRodgers; BTycko; SIWang; MHWigler; CYen;

727

Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1.

2010: Cancer Genome Atlas Research Network; GAlexe; CBrennan; LDing; HSFeiler; SGabriel; GGetz; TGolub; ... JWGray; SGupta; DNHayes; KAHoadley; JGHodgson; LJakkula; CDJames; AKahn; MLawrence; JPMesirov; MMeyerson; CRMiller; MO'Kelly; CMPerou; EPurdom; YQi; JNSarkaria; TPSpeed; PTSpellman; PTamayo; RGVerhaak; VWang; BAWeir; MDWilkerson; RKWilson; WWinckler;

719

Identification of a cancer stem cell in human brain tumors.

2003: VEBonn; IDClarke; PBDirks; CHawkins; SKSingh; JSquire; MTerasaki;

682

MGMT gene silencing and benefit from temozolomide in glioblastoma.

2005: JEBromberg; JGCairncross; Nde Tribolet; ACDiserens; TGorlia; JAHainfellner; MFHamou; PHau; ... MEHegi; RCJanzer; JMKros; LMariani; WMason; ROMirimanoff; RStupp; MWeller;

595

High frequency of mutations of the PIK3CA gene in human cancers.

2004: ABardelli; AGazdar; KWKinzler; SMarkowitz; SMPowell; JPtak; GJRiggins; YSamuels; ... NSilliman; SSzabo; VEVelculescu; BVogelstein; ZWang; JKWillson; HYan;

594

Integrative genomics viewer.

2011: GGetz; MGuttman; ESLander; JPMesirov; JTRobinson; HThorvaldsdóttir; WWinckler;

593

IDH1 and IDH2 mutations in gliomas.

2009: IBatinic-Haberle; DDBigner; AFriedman; HFriedman; JHerndon; GJin; SJones; KWKinzler; ... IKos; RMcLendon; DWParsons; BARasheed; DReardon; GJRiggins; VEVelculescu; BVogelstein; HYan; WYuan;

503

Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis.

1992: AItin; EKeshet; DShweiki; DSoffer;

503

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial.

2009: European Organisation for Research and Treatment of Cancer Brain Tumour and Radiation Oncology Groups; National Cancer Institute of Canada Clinical Trials Group; AAllgeier; KBelanger; AABrandes; JGCairncross; EEisenhauer; BFisher; ... JGijtenbeek; TGorlia; PHau; MEHegi; RCJanzer; DLacombe; SKLudwin; CMarosi; WPMason; ROMirimanoff; KMokhtari; RStupp; MJTaphoorn; MJvan den Bent; CJVecht; SVilla; MWeller; PWesseling;

499

MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells.

2005: JAChan; KSKosik; AMKrichevsky;

469

An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors.

2008: GWBell; IBen-Porath; VJCarey; RGe; ARegev; MWThomson; RAWeinberg;

467

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers.

1997: MLBaumgard; TDavis; CFrye; THattier; RHu; SAJasser; LALangford; AHLigon; ... HLin; MAPershouse; PASteck; BSwedlund; SVTavtigian; DHTeng; WKYung;

422

Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines.

2006: NChristopher; NMDonin; HAFine; YKotliarov; SKotliarova; JLee; ALi; JKPark; ... SPastorino; BWPurow; QSu; WZhang;

406

Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma.

2004: EBinda; BCipelletti; SDe Vitis; FDiMeco; RFiocco; CForoni; RGalli; AGritti; UOrfanelli; AVescovi;

405

Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo.

1993: MArmanini; NFerrara; NGillett; KJKim; BLi; HSPhillips; JWiner;

404

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers.

2008: XOBreakefield; BSCarter; WTCurry; LGainche; AMKrichevsky; DHMeijer; MSena-Esteves; JSkog; Svan Rijn; TWürdinger;

399