Top 20 of Gout

Article title # Publications/# Citations

Gout-associated uric acid crystals activate the NALP3 inflammasome.

2006: FMartinon; AMayor; VPetrilli; ATardivel; JTschopp;

539

Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part II.

2008: National Arthritis Data Workgroup; LMArnold; HChoi; RADeyo; DTFelson; SGabriel; CGHelmick; RHirsch; ... MCHochberg; GGHunder; JMJordan; JNKatz; HMKremers; RCLawrence; FWolfe;

406

High association of an HL-A antigen, W27, with ankylosing spondylitis.

1973: RBluestone; CMPearson; LSchlosstein; PITerasaki;

166

A FAMILIAL DISORDER OF URIC ACID METABOLISM AND CENTRAL NERVOUS SYSTEM FUNCTION.

1964: MLesch; WLNyhan;

120

SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout.

2008: MAringer; LBarac-Lauc; ZBiloglav; HCampbell; SCampbell; LADonnelly; LDFairbanks; JFloyd; ... BGorgoni; JGraessler; NKGray; NDHastie; CHayward; PHohenstein; BJanićijević; CHKimber; IMKlaric; SAKnott; IKolcic; AMarinaki; PMMcKeigue; JMorgan; ADMorris; CNPalmer; MPericic; OPolasek; SHRalston; WARichardson; PLRiches; IRudan; PRudan; XShu; TŠkarić-Jurić; NSmolej-Narancić; ATenesa; VVitart; SHWild; JFWilson; AFWright; LZgaga;

120

The NLRP3 inflammasome: a sensor for metabolic danger?

2010: KSchroder; JTschopp; RZhou;

119

Preliminary criteria for the classification of the acute arthritis of primary gout.

1977: JLDecker; ATMasi; DJMcCarty; HRobinson; SLWallace; TFYu;

107

Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations.

2009: ENGAGE Consortium; EUROSPAN consortium; KORA Study; PROCARDIS Consortium; WTCCC; JAdamski; EAlbrecht; YAulchenko; ... JSBeckmann; SBergmann; MBochud; MBrown; HCampbell; MCaulfield; JConnell; ADoering; ADominiczak; MFarrall; CGieger; UGyllensten; GHomuth; TIllig; ÅJohansson; TJohnson; MKolz; CLamina; MMangino; MIMcCarthy; TMeitinger; VMooser; PMunroe; RNagaraja; MNauck; DRNyholt; JPeden; LPeltonen; MPerola; PPramstaller; HProkisch; IRudan; PSalo; VSalomaa; NJSamani; SSanna; DSchlessinger; TDSpector; ATeumer; MUda; VVitart; UVölker; PVollenweider; HVölzke; GWaeber; CWallace; RWang-Sattler; DWaterworth; HWatkins; JBWhitfield; HEWichmann; JFWilson; AFWright;

103

Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study.

2008: BCAstor; EJBenjamin; EBoerwinkle; JCoresh; ADehghan; CSFox; AHofman; SJHwang; ... WLKao; AKöttgen; DLevy; FRivadeneira; CMvan Duijn; JCWitteman; QYang;

101

SLC2A9 influences uric acid concentrations with pronounced sex-specific effects.

2008: SCoassin; ADöring; GFischer; CGieger; HGohlke; KHenke; TIllig; NKlopp; ... FKronenberg; DMehta; CMeisinger; TMeitinger; BPaulweber; APfeufer; HProkisch; DRosskopf; HVölzke; HEWichmann;

93

Febuxostat compared with allopurinol in patients with hyperuricemia and gout.

2005: MABecker; DEustace; NJoseph-Ridge; PAMacDonald; WAPalo; HRSchumacher; JStreit; RLWortmann;

83

EULAR evidence based recommendations for gout. Part II: Management. Report of a task force of the EULAR Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT).

2006: EULAR Standing Committee for International Clinical Studies Including Therapeutics; TBardin; VBarskova; PConaghan; MDoherty; JGerster; JJacobs; BLeeb; ... FLioté; GMcCarthy; PNetter; GNuki; EPascual; FPerez-Ruiz; APignone; JPimentao; LPunzi; ERoddy; TUhlig; WZhang; IZimmermann-Gorska;

78

The degree of masculine differentiation of obesities: a factor determining predisposition to diabetes, atherosclerosis, gout, and uric calculous disease.

1956 Jan-Feb: JVague;

78

MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals.

2006: SAkira; CJChen; KFitzgerald; DGolenbock; AHearn; GReed; KLRock; YShi;

76

Pathogenesis of gout.

2005: American College of Physicians; American Physiological Society; HKChoi; DBMount; AMReginato;

74

Purine-rich foods, dairy and protein intake, and the risk of gout in men.

2004: KAtkinson; HKChoi; GCurhan; EWKarlson; WWillett;

71

Prevalence of gout and hyperuricemia in the US general population: the National Health and Nutrition Examination Survey 2007-2008.

2011: HKChoi; BJPandya; YZhu;

65

A specific enzyme defect in gout associated with overproduction of uric acid.

1967: JFHenderson; WNKelley; FMRosenbloom; JESeegmiller;

64

Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout.

2009: EBoerwinkle; JCoresh; WBGuggino; AKöttgen; MKöttgen; OMWoodward;

61

HEMOLYTIC COMPLEMENT IN SYNOVIAL FLUID.

1964: TJPekin; NJZvaifler;

60