Top 20 of Insulin Resistance

Article title # Publications/# Citations

Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man.

1985: JPHosker; DRMatthews; BANaylor; ASRudenski; DFTreacher; RCTurner;

2453

Inflammation and metabolic disorders.

2006: GSHotamisligil;

951

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance.

2003: GTBarnes; HChen; CJChou; ANichols; JSRoss; JSole; GTan; LATartaglia; ... HXu; DYang; QYang;

930

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.

2007: Diabetes Genetics Initiative of Broad Institute of Harvard and MIT, Lund University, and Novartis Institutes of BioMedical Research; PAlmgren; DAltshuler; KArdlie; RBarry; KBengtsson Boström; ABerglund; BBlumenstiel; ... WBrodeur; NPBurtt; JCamarata; JCarlson; HChen; NChia; GWChirn; MJDaly; PIde Bakker; MDeFelice; MFava; JCFlorez; SBGabriel; DGage; CGates; LGianniny; JGibbons; LGroop; CGuiducci; RHackett; LHall; BHandsaker; CHealy; JNHirschhorn; JHolmkvist; TEHughes; BIsomaa; SKathiresan; ELaurila; GLettre; ULindblad; HNLyon; VLyssenko; QMa; OMelander; JMeyer; CNewton-Cheh; KNguyen; PNilsson; MNizzari; MOrho-Melander; HParikh; MParkin; SPurcell; LRåstam; DRichardson; DRicke; JJRoix; RSaxena; MSjögren; CSougnez; EKSpeliotes; MSterner; ASurti; MSvensson; MSvensson; MRTaskinen; RTewhey; TTuomi; BFVoight;

815

Banting lecture 1988. Role of insulin resistance in human disease.

1988: GMReaven;

803

Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation.

1998: KGAlberti; PZZimmet;

803

Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance.

1993: GSHotamisligil; NSShargill; BMSpiegelman;

744

Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity.

2009: American Heart Association; Hational Heart, Lung, and Blood Institute; International Association for the Study of Obesity; International Atherosclerosis Society; International Diabetes Federation Task Force on Epidemiology and Prevention; World Heart Federation; KGAlberti; JICleeman; ... KADonato; RHEckel; JCFruchart; SMGrundy; WPJames; CMLoria; SCSmith; PZZimmet;

665

Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha.

2006: CArgmann; JAuwerx; FDaussin; PElliott; BGeny; ZGerhart-Hines; MLaakso; MLagouge; ... PLambert; CLerin; NMessadeq; HMeziane; JMilne; PPuigserver;

597

Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes.

2004: QCao; LHGlimcher; CGorgun; GSHotamisligil; NNIwakoshi; AHLee; UOzcan; EOzdelen; GTuncman; EYilmaz;

579

Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp.

1999: RADeFronzo; MMatsuda;

542

Inflammation and insulin resistance.

2006: ABGoldfine; JLee; SEShoelson;

538

A central role for JNK in obesity and insulin resistance.

2002: LChang; CZGorgun; JHirosumi; GSHotamisligil; MKarin; KMaeda; GTuncman; KTUysal;

532

Insulin signalling and the regulation of glucose and lipid metabolism.

2001: CRKahn; ARSaltiel;

523

TLR4 links innate immunity and fatty acid-induced insulin resistance.

2006: JSFlier; KInouye; MVKokoeva; HShi; ITzameli; HYin;

509

Inflammation, stress, and diabetes.

2005: GSHotamisligil; KEWellen;

475

The metabolic syndrome.

2005 Apr 16-22: RHEckel; SMGrundy; PZZimmet;

469

Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes.

2006: MFuruhashi; CZGorgun; GSHotamisligil; LOzcan; UOzcan; ROSmith; ÉVaillancourt; EYilmaz;

451

The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity.

2001: YAkanuma; OEzaki; PFroguel; OGavrilova; KHara; TIde; TKadowaki; HKagechika; ... JKamon; SKimura; NKubota; YMori; KMurakami; RNagai; YNakano; MLReitman; KShudo; YTerauchi; KTobe; MTomita; NTsuboyama-Kasaoka; CVinson; HWaki; TYamauchi; MYoda;

442

The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus.

1963: PBGarland; CNHales; EANewsholme; PJRandle;

431