Top 20 of Lupus Nephritis

Article title # Publications/# Citations

Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor.

1999: HHiai; THonjo; NMinato; HNishimura; MNose;

238

Copy number polymorphism in Fcgr3 predisposes to glomerulonephritis in rats and humans.

2006: TJAitman; GBhangal; JJBoyle; HTCook; PRCook; JDomin; RDong; MDuda; ... DJEvans; JFlint; MDHodges; MDJohnson; JMangion; AJMarshall; PJNorsworthy; SGPatel; EPetretto; CDPusey; CRoberton-Lowe; KSheehan-Rooney; JSmith; TJVyse;

188

Anti-neutrophil cytoplasmic autoantibodies with specificity for myeloperoxidase in patients with systemic vasculitis and idiopathic necrotizing and crescentic glomerulonephritis.

1988: RJFalk; JCJennette;

171

Systemic lupus erythematosus.

2011: GCTsokos;

140

Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus.

2005: SAkira; LAlexopoulou; SRChristensen; RAFlavell; MKashgarian; MJShlomchik;

116

Features of systemic lupus erythematosus in Dnase1-deficient mice.

2000: HKarsunky; HGMannherz; TMöröy; MNapirei; HStephan; BZevnik;

104

Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis.

2010: UAAbed; KAmann; VBrinkmann; BGFürnrohr; AHakkim; MHerrmann; BLaube; REVoll; AZychlinsky;

103

Tumour necrosis factor-alpha in murine autoimmune 'lupus' nephritis.

1988: COJacob; HOMcDevitt;

93

Polygenic control of susceptibility to murine systemic lupus erythematosus.

1994: JALongmate; LMorel; UHRudofsky; JSchiffenbauer; EKWakeland;

92

Uncoupling of immune complex formation and kidney damage in autoimmune glomerulonephritis.

1998: RClynes; CDumitru; JVRavetch;

88

Genetic reconstitution of systemic lupus erythematosus immunopathology with polycongenic murine strains.

2000: KRBlenman; BPCroker; GGilkeson; GHuang; CMohan; LMorel; EKWakeland;

81

Netting neutrophils induce endothelial damage, infiltrate tissues, and expose immunostimulatory molecules in systemic lupus erythematosus.

2011: CCBerthier; ATBruce; LChaperot; MFDenny; JBHodgin; MJKaplan; RKhandpur; MKlinker; ... MKretzler; AMLin; SHOlsen; JPlumas; CJRubin; DShealy; EVillanueva; SYalavarthi; WZhao;

81

Mycophenolate mofetil or intravenous cyclophosphamide for lupus nephritis.

2005: GBAppel; CAranow; JBuyon; MADooley; GSGilkeson; EMGinzler; MYKim; JTMerrill; ... MPetri; DJWallace; MHWeisman;

74

Treatment of lupus-prone mice with a dual inhibitor of TLR7 and TLR9 leads to reduction of autoantibody production and amelioration of disease symptoms.

2007: FJBarrat; JHChan; RLCoffman; CGuiducci; TMeeker;

73

T cell receptor alpha/beta expressing double-negative (CD4-/CD8-) and CD4+ T helper cells in humans augment the production of pathogenic anti-DNA autoantibodies associated with lupus nephritis.

1989: SKDatta; SShivakumar; GCTsokos;

72

IL-21 has a pathogenic role in a lupus-prone mouse model and its blockade with IL-21R.Fc reduces disease progression.

2007: TPBrown; MCollins; KDunussi-Joannopoulos; DHerber; SLiang; DAYoung;

70

Induction of B7-1 in podocytes is associated with nephrotic syndrome.

2004: KAsanuma; NCalvaresi; ADavidson; CFaul; LGiardino; RKalluri; JAKreidberg; MKretzler; ... MLoos; PMundel; JOh; MPRastaldi; JReiser; KSchwarz; AHSharpe; HSugimoto; GVon Gersdorff; HWatanabe;

67

The role of B cells in lpr/lpr-induced autoimmunity.

1994: DHuszar; MPMadaio; DNi; MJShlomchik; MTrounstein;

67

Association of increased interferon-inducible gene expression with disease activity and lupus nephritis in patients with systemic lupus erythematosus.

2006: EBrahn; WChen; XDong; XFeng; JDFitzGerald; DEFurst; AGorn; JMGrossman; ... BHHahn; PHanvivadhanakul; MHKim; MMcMahon; GSPark; MTaylor; BPTsao; HHWeng; HWu;

65

Efficacy of mycophenolate mofetil in patients with diffuse proliferative lupus nephritis. Hong Kong-Guangzhou Nephrology Study Group.

2000: KWChan; TMChan; GXFang; YLJi; KNLai; CSLau; FKLi; CSTang; ... MKTong; AKWong; RWWong;

61