Top 20 of Metabolic Diseases

Article title # Publications/# Citations

"Mini-mental state". A practical method for grading the cognitive state of patients for the clinician.

1975: MFFolstein; SEFolstein; PRMcHugh;

6493

Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey.

2002: WHDietz; ESFord; WHGiles;

684

A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine.

2005: DCWallace;

612

mTOR signaling in growth control and disease.

2012: MLaplante; DMSabatini;

598

Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha.

2006: CArgmann; JAuwerx; FDaussin; PElliott; BGeny; ZGerhart-Hines; MLaakso; MLagouge; ... PLambert; CLerin; NMessadeq; HMeziane; JMilne; PPuigserver;

597

Adapting proteostasis for disease intervention.

2008: WEBalch; ADillin; JWKelly; RIMorimoto;

422

Mitochondrial diseases in man and mouse.

1999: DCWallace;

377

Endoplasmic reticulum stress and the inflammatory basis of metabolic disease.

2010: GSHotamisligil;

320

Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta.

1997: JChen; RMEvans; BMForman;

279

Mitochondria: dynamic organelles in disease, aging, and development.

2006: DCChan;

278

The endocannabinoid system as an emerging target of pharmacotherapy.

2006: SBatkai; GKunos; PPacher;

266

Mammalian sirtuins: biological insights and disease relevance.

2010: MCHaigis; DASinclair;

262

ER stress and the unfolded protein response.

2005: RJKaufman; MSchröder;

233

Inflammatory mechanisms in obesity.

2011: MFGregor; GSHotamisligil;

227

Five years of GWAS discovery.

2012: MABrown; MIMcCarthy; PMVisscher; JYang;

222

Roles of PPARs in health and disease.

2000: BDesvergne; SKersten; WWahli;

201

HMDB: the Human Metabolome Database.

2007: GAmegbey; DArndt; FBamforth; DBlock; DCheng; MClements; DClive; MACoutouly; ... RDowlatabadi; GEDuggan; REisner; IForsythe; CFung; MGebremedhin; RGreiner; ACGuo; NGuo; DDHau; KJeroncic; KJewell; CKnox; MLewis; LLi; GDMacinnis; TMarrie; JMiniaci; LNikolai; LQuerengesser; SSawhney; SShrivastava; PStothard; BDSykes; PTang; DTzur; HJVogel; JWagner; AMWeljie; DSWishart; NYoung; YZhang;

199

Specific SIRT1 activation mimics low energy levels and protects against diet-induced metabolic disorders by enhancing fat oxidation.

2008: JAuwerx; CCantó; PJElliott; JNFeige; SMHouten; MLagouge; PDLambert; CMataki; JCMilne; AStrehle;

180

The inflammasome NLRs in immunity, inflammation, and associated diseases.

2011: BKDavis; JPTing; HWen;

171

The preventable causes of death in the United States: comparative risk assessment of dietary, lifestyle, and metabolic risk factors.

2009: GDanaei; ELDing; MEzzati; DMozaffarian; CJMurray; JRehm; BTaylor;

170