Top 20 of Nerve Degeneration

Article title # Publications/# Citations

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics.

2002: JHardy; DJSelkoe;

1558

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide.

2007: CHaass; DJSelkoe;

676

Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17.

1998: JAdamson; AAndreadis; MBaker; HBasun; SChakraverty; LKChe; DCraufurd; FDark; ... PDavies; Ede Graaff; DDickson; PRDodd; SFahn; SFroelich; AGoate; AGrover; JHackett; JHardy; NHayward; PHeutink; MHillebrand; HHoulden; MHutton; AIsaacs; MJoosse; JBKwok; JMKwon; LLannfelt; CLLendon; SLincoln; TLynch; DMann; JCMorris; DNeary; MNeystat; JNorton; PNowotny; BAOostra; FOwen; RCPetersen; SPickering-Brown; LAReed; PRizzu; PRSchofield; JSnowden; MStevens; TTannenberg; JTrojanowski; Jvan Baren; Jvan Swieten; EWauters;

481

The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia.

2004: JAlegre; IAmpuero; BAtarés; JGde Yébenes; TDel Ser; EGomez Tortosa; JCGómez-Esteban; JHoenicka; ... ELezcano; VLlorens; DGMunoz; ORodríguez; RRos; LVidal; JJZarranz;

400

Chronic systemic pesticide exposure reproduces features of Parkinson's disease.

2000: RBetarbet; MGarcia-Osuna; JTGreenamyre; GMackenzie; AVPanov; TBSherer;

396

Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology.

2004: FAsmus; SBiskup; DBCalne; ICCarbajal; DWDickson; MFarrer; TGasser; MHulihan; ... JKachergus; PLeitner; PLichtner; SLincoln; TMeitinger; BMüller-Myhsok; NPatenge; RFPfeiffer; AJStoessl; TMStrom; RJUitti; PVieregge; ZKWszolek; AZimprich;

386

Pathobiology of ischaemic stroke: an integrated view.

1999: UDirnagl; CIadecola; MAMoskowitz;

369

High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation.

2000: KHu; KJohnson-Wood; DKholodenko; MMallory; EMasliah; LMcConlogue; LMucke; EMRockenstein; GTatsuno; GQYu;

335

Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin.

2006: EBae; JChung; JKim; JMKim; SKim; YKim; SBLee; SLee; ... JPark; MShong; SSong;

325

Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders.

2003: BCaughey; PTLansbury;

315

Diffusion tensor imaging detects and differentiates axon and myelin degeneration in mouse optic nerve after retinal ischemia.

2003: AHCross; WKJu; SJLin; AHNeufeld; SKSong; SWSun;

287

El Escorial revisited: revised criteria for the diagnosis of amyotrophic lateral sclerosis.

2000: World Federation of Neurology Research Group on Motor Neuron Diseases; BRBrooks; RGMiller; TLMunsat; MSwash;

278

Mitochondria: dynamic organelles in disease, aging, and development.

2006: DCChan;

278

Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models.

2006: BBhullar; NMBonini; GACaldwell; KACaldwell; SCao; ACashikar; AACooper; ADGitler; ... CMHaynes; KJHill; RDKolodner; JLaBaer; SLindquist; FLiu; KLiu; GMarsischky; JCRochet; KEStrathearn; KXu;

263

Molecular pathways of neurodegeneration in Parkinson's disease.

2003: TMDawson; VLDawson;

256

A Drosophila model of Parkinson's disease.

2000: WWBender; MBFeany;

255

Tau-mediated neurodegeneration in Alzheimer's disease and related disorders.

2007: CBallatore; VMLee; JQTrojanowski;

254

Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

1998: DDevys; SFinkbeiner; MEGreenberg; FSaudou;

246

Unraveling the mechanisms involved in motor neuron degeneration in ALS.

2004: LIBruijn; DWCleveland; TMMiller;

241

Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila.

2001: BLApostol; LBodai; MGreenwald; DEHousman; GRJackson; AKazantsev; RKurokawa; JLMarsh; ... AMcCampbell; JPallos; MPoelman; ESchmidt; JSSteffan; LMThompson; YZZhu;

231