Top 20 of Nevus

Article title # Publications/# Citations

BRAFE600-associated senescence-like cell cycle arrest of human naevi.

2005: CDenoyelle; TKuilman; DMMajoor; CMichaloglou; WJMooi; DSPeeper; JWShay; MSSoengas; CMvan der Horst; LCVredeveld;

395

High frequency of BRAF mutations in nevi.

2002: PDuray; KSHansen; ULHarper; NKHayward; PHeenan; GHostetter; JKakareka; OKallioniemi; ... PSMeltzer; TYMoses; TPohida; PMPollock; CMRobbins; GSalem; MStark; JMTrent; UWagner; LMYudt;

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Melanoma.

2006: MCMihm; AJMiller;

158

Oncogenic Braf induces melanocyte senescence and melanoma in mice.

2009: Sda Rocha Dias; VDelmas; NDhomen; RHayward; LLarue; RMarais; CPritchard; JSReis-Filho; KSavage;

112

Mutations in GNA11 in uveal melanoma.

2010: GBaimukanova; BCBastian; NBouvier; KBusam; MBCrosby; IDolgalev; MCGarrido; GGreen; ... KGGriewank; AHeguy; RKhanin; JO'Brien; ACObenauf; RRoy; MMSozen; MRSpeicher; CDVan Raamsdonk; SVemula; WWackernagel; TWiesner;

104

BRAF mutations are sufficient to promote nevi formation and cooperate with p53 in the genesis of melanoma.

2005: JFAmatruda; JCAster; SBerghmans; DEFisher; CDFletcher; SRGranter; KRKopani; JLKutok; ... CLee; ATLook; EAMayhall; RDMurphey; EEPatton; DTraver; HRWidlund; LIZon;

96

Ataxia telangiectasia: a human mutation with abnormal radiation sensitivity.

1975: CFArlett; BABridges; SAHarcourt; DGHarnden; ARLehmann; SStevens; AMTaylor;

89

The gene expression signatures of melanoma progression.

2005: REAllen; JCrothers; SFederman; CHaqq; MKashani-Sabet; DKhodabakhsh; SPLeong; BMLjung; ... JRMiller; MNosrati; BLPulliam; RWSagebiel; MISinger; DSudilovsky;

75

Cellular senescence in naevi and immortalisation in melanoma: a role for p16?

2006: ZAAbdel-Malek; DCBennett; SCCheong; HChong; JChow; VCGray-Schopfer; RMarais; TMoss; DWynford-Thomas;

68

The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset.

2011: SAit-Si-Ali; VBattisti; RBeroukhim; SBilodeau; CBourque; CJBurke; CJCeol; FFerrè; ... LFritsch; LAGarraway; TJHollmann; YHouvras; JJane-Valbuena; LAJohnson; WMLin; MLoda; CHMermel; DAOrlando; LTurner; AUong; RAYoung; LIZon;

66

Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma.

2012: CCeol; KDresser; LMDuncan; RFang; YHouvras; DHu; YHu; UBKaiser; ... HKakavand; AJKhorasani; SKleffel; ALarson; CWLee; CLezcano; BQLian; CGLian; MCMihm; GFMurphy; JNeiswender; TSchatton; RAScolyer; YGShi; LTan; JFThompson; BAWoda; FWu; WXu; YXu; YYang; QZhan; LIZon;

63

Meta-analysis of risk factors for cutaneous melanoma: I. Common and atypical naevi.

2005: DAbeni; PBoyle; MSCattaruzza; SGandini; CFMelchi; PPasquini; FSera;

61

Keratins and the skin.

1995: EFuchs;

59

Genome-wide association study identifies variants at 9p21 and 22q13 associated with development of cutaneous nevi.

2009: JHBarrett; VBataille; DTBishop; JABishop; ACervino; PDeloukas; DLDuffy; DEElder; ... MFalchi; NKHayward; NGMartin; GWMontgomery; TPastinen; NSoranzo; TDSpector; ZZZhao;

57

In vivo confocal scanning laser microscopy of human skin: melanin provides strong contrast.

1995: RRAnderson; DEsterowitz; MGrossman; MRajadhyaksha; RHWebb;

53

Increased expression of stem cell markers in malignant melanoma.

2006: WMKlein; AJKlein-Szanto; SRTahan; BPWu; HWu; SZhao;

52

Prognostic significance of activated Akt expression in melanoma: a clinicopathologic study of 292 cases.

2005: DLDai; GLi; MMartinka;

48

Loss-of-function mutations in LEMD3 result in osteopoikilosis, Buschke-Ollendorff syndrome and melorheostosis.

2004: TCosta; PJCoucke; ADe Paepe; PDebeer; JHellemans; DHuylebroeck; KJanssens; BMenten; ... GRMortier; JMNaeyaert; OPreobrazhenska; RSavarirayan; FSpeleman; WVan Hul; NVan Roy; JVandesompele; FVanhoenacker; PCVerdonk; SJVermeulen; KVerschueren; AWillaert;

44

Characteristics of cultured human melanocytes isolated from different stages of tumor progression.

1985: GBalaban; JLBennicelli; EBondi; WHClark; DEElder; DGuerry; DHerlyn; MHerlyn; PNowell; JThurin;

42

Human keratin diseases: the increasing spectrum of disease and subtlety of the phenotype-genotype correlation.

1999: ADIrvine; WHMcLean;

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