Top 20 of Nevus, Pigmented

Article title # Publications/# Citations

Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7.

2008: MRGreen; MMahalingam; RWSerra; NWajapeyee; XZhu;

190

The histogenesis and biologic behavior of primary human malignant melanomas of the skin.

1969: EABernardino; WHClark; LFrom; MCMihm;

133

A study of tumor progression: the precursor lesions of superficial spreading and nodular melanoma.

1984: WHClark; DEElder; MNEpstein; MHGreene; DGuerry; MVan Horn;

79

Germline mutations in BAP1 predispose to melanocytic tumors.

2011: DAbramson; BCBastian; JCBecker; LCerroni; IFried; KGGriewank; HKutzner; AELash; ... SLoy; RMurali; ACObenauf; KOffit; AOtt; GPalmedo; MPirun; ARütten; NDSocci; MRSpeicher; PUlz; AViale; WWackernagel; TWiesner; CWindpassinger; IWolf;

51

NRAS and BRAF mutations in melanoma tumours in relation to clinical characteristics: a study based on mutation screening by pyrosequencing.

2006: EEdlundh-Rose; SEgyhazi; JHansson; JLundeberg; EMånsson-Brahme; KOmholt; APlatz;

48

Mitogen-actived protein kinase activation is an early event in melanoma progression.

2002: JLArbiser; FCerimele; CCohen; GCotsonis; BGovindarajan; NMacaron; JHSequeira; DGSexton; MShoji; AZavala-Pompa;

45

Origin of familial malignant melanomas from heritable melanocytic lesions. 'The B-K mole syndrome'.

1978: AMAinsworth; WHClark; MGreene; MJMastrangelo; RRReimer;

43

ASSOCIATION OF WILMS'S TUMOR WITH ANIRIDIA, HEMIHYPERTROPHY AND OTHER CONGENITAL MALFORMATIONS.

1964: JFFraumeni; MDManning; RWMiller;

39

Signatures of microRNAs and selected microRNA target genes in human melanoma.

2010: IBehrmann; SKreis; CMargue; DMoser; AMuller; DNashan; PVNazarov; DPhilippidou; MSchmitt; LVallar;

38

A major quantitative-trait locus for mole density is linked to the familial melanoma gene CDKN2A: a maximum-likelihood combined linkage and association analysis in twins and their sibs.

1999: JFAitken; DLDuffy; AEldridge; MGrace; ACGreen; NKHayward; NGMartin; CMayne; ... MCNeale; LO'Gorman; GZhu;

37

Melanocytic nevi, solar keratoses, and divergent pathways to cutaneous melanoma.

2003: ACGreen; NKHayward; MCHughes; DMPurdie; PWatt; DCWhiteman;

36

BRAF oncogenic mutations correlate with progression rather than initiation of human melanoma.

2003: SAAaronson; OBenard; JDong; RGPhelps; RQiao; ZRonai; SYao;

35

A three-single-nucleotide polymorphism haplotype in intron 1 of OCA2 explains most human eye-color variation.

2006: WChen; DLDuffy; NKHayward; MRJames; LLe; NGMartin; GWMontgomery; RASturm; ZZZhao;

34

Monoclonal antibodies specific for melanocytic tumors distinguish subpopulations of melanocytes.

1986: FGough; AMGown; DHoak; MAMcNutt; AMVogel;

34

Nucleolar organiser region associated proteins in cutaneous melanotic lesions: a quantitative study.

1987: JCrocker; NSkilbeck;

34

Congenital melanocytic nevi frequently harbor NRAS mutations but no BRAF mutations.

2006: BCBastian; JBauer; JACurtin; DPinkel;

31

Classifying melanocytic tumors based on DNA copy number changes.

2003: BCBastian; PELeBoit; ABOlshen; DPinkel;

30

MicroRNA-15b represents an independent prognostic parameter and is correlated with tumor cell proliferation and apoptosis in malignant melanoma.

2010: RGutzmer; AKapp; UKuettler; AMattern; ISatzger; BVoelker; DWeinspach;

30

Discordance in the histopathologic diagnosis of melanoma and melanocytic nevi between expert pathologists.

1996: ERFarmer; RGonin; MPHanna;

29

BRAF and NRAS mutations in melanoma and melanocytic nevi.

2006: JTElder; DRFullen; SBGruber; TMJohnson; RPNair; JNPoynter; BRedman; MSSoengas; NEThomas;

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