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538201 to 538300 most common queries
List represents a sample of symptoms, diseases, and other queries. Updated weekly.
The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate.
BreakDancer: an algorithm for high-resolution mapping of genomic structural variation.
Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia.
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia.
Proposals for the classification of the acute leukaemias. French-American-British (FAB) co-operative group.
Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo.
A block to elongation is largely responsible for decreased transcription of c-myc in differentiated HL60 cells.
Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet.
DNMT3A mutations in acute myeloid leukemia.
Revised recommendations of the International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid Leukemia.
Terminal differentiation of human promyelocytic leukemia cells induced by dimethyl sulfoxide and other polar compounds.
The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized.
Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation.
DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome.
Recurring mutations found by sequencing an acute myeloid leukemia genome.
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell.
Nilotinib in imatinib-resistant CML and Philadelphia chromosome-positive ALL.
BCR-ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros.
Graft-versus-leukemia reactions after bone marrow transplantation.
Support vector machine classification and validation of cancer tissue samples using microarray expression data.
Oncogenic transcription factors in the human acute leukemias.
Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl.
Specific proteolytic cleavage of poly(ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis.
Treatment of acute lymphoblastic leukemia.
Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias.
MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia.
Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome.
ABT-263: a potent and orally bioavailable Bcl-2 family inhibitor.
Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling.
A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency.
Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia.
Diagnosis of multiple cancer types by shrunken centroids of gene expression.
The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease.
Molecular classification of cancer: class discovery and class prediction by gene expression monitoring.
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.
Chronic radial head dislocation in children, Part 1: pathologic changes preventing stable reduction and surgical correction.
Changes in the management of monteggia fractures.
Transolecranon fracture-dislocation of the elbow.
The problem of Monteggia fracture-dislocations in children.
The Monteggia lesion in children. Fracture of the ulna and dislocation of the radial head.
Monteggia injuries in children.
Altered Mental Status, Syncope
Corrective ulnar osteotomy for malunited anterior Monteggia lesions in children. 12 patients followed for 1-12 years.
Complex elbow instability.
Chronic radial head dislocation in children, Part 2: results of open treatment and factors affecting final outcome.
Treatment of chronic post-traumatic dislocation of the radial head in children.
Surgical treatment of symptomatic chronic radial head dislocation: a neglected Monteggia fracture.
Monteggia fracture-dislocations in children.
Missed chronic anterior Monteggia lesion. Closed reduction by gradual lengthening and angulation of the ulna.
Chronic posttraumatic anterior dislocation of the radial head in children: thirteen cases treated by open reduction, ulnar osteotomy, and annular ligament reconstruction through a Boyd incision.
Chronic Monteggia lesions in children. Complications and results of reconstruction.
Compression-plate fixation in acute diaphyseal fractures of the radius and ulna.
Unstable fracture-dislocations of the forearm (Monteggia and Galeazzi lesions).
Treatment of the missed Monteggia fracture in the child.
Pediatric fractures of the forearm.
Leishmaniasis--current chemotherapy and recent advances in the search for novel drugs.
Leishmaniasis and poverty.
Leishmaniasis. Public health aspects and control.
Splenic accumulation of IL-10 mRNA in T cells distinct from CD4+CD25+ (Foxp3) regulatory T cells in human visceral leishmaniasis.
Oral miltefosine for Indian visceral leishmaniasis.
Molecular characterization of a kinesin-related antigen of Leishmania chagasi that detects specific antibody in African and American visceral leishmaniasis.
Absence of gamma interferon and interleukin 2 production during active visceral leishmaniasis.
Failure of pentavalent antimony in visceral leishmaniasis in India: report from the center of the Indian epidemic.
In vivo cytokine profiles in patients with kala-azar. Marked elevation of both interleukin-10 and interferon-gamma.
Macrophage microbicidal mechanisms in vivo: reactive nitrogen versus oxygen intermediates in the killing of intracellular visceral Leishmania donovani.
Immunological phenomena in leprosy and related diseases.
The increase in risk factors for leishmaniasis worldwide.
Interleukin 10 production correlates with pathology in human Leishmania donovani infections.
Visceral leishmaniasis: current status of control, diagnosis, and treatment, and a proposed research and development agenda.
Killing of intracellular Leishmania donovani by lymphokine-stimulated human mononuclear phagocytes. Evidence that interferon-gamma is the activating lymphokine.
The Ity/Lsh/Bcg locus: natural resistance to infection with intracellular parasites is abrogated by disruption of the Nramp1 gene.
Comparative genomic analysis of three Leishmania species that cause diverse human disease.
Visceral leishmaniasis: what are the needs for diagnosis, treatment and control?
Leishmaniasis: current situation and new perspectives.
Free radicals and Dupuytren's contracture.
Dupuytren's contracture: an audit of the outcomes of surgery.
Dupuytren's contracture, alcohol consumption, and chronic liver disease.
Dupuytren's contracture unfolded.
THE GENETIC FACTOR IN DUPUYTREN'S DISEASE.
Management of Dupuytren's disease--clear advice for an elusive condition.
Injectable collagenase Clostridium histolyticum: a new nonsurgical treatment for Dupuytren's disease.
Genetics of Dupuytren's disease.
The pathology of frozen shoulder. A Dupuytren-like disease.
Dupuytren disease: Anatomy, pathology, presentation, and treatment.
Epidemiology of Dupuytren's disease.
Epidemiology of Dupuytren's disease: clinical, serological, and social assessment. The Reykjavik Study.
Efficacy and safety of injectable mixed collagenase subtypes in the treatment of Dupuytren's contracture.
Dupuytren's contracture; a new concept of the pathogenesis correlated with surgical management.
Increased formation of pyridinoline cross-links due to higher telopeptide lysyl hydroxylase levels is a general fibrotic phenomenon.
Dupuytren's disease and frozen shoulder induced by treatment with a matrix metalloproteinase inhibitor.
Biochemical changes in the collagen of the palmar fascia in patients with Dupuytren's disease.
Beta-catenin signaling in fibroproliferative disease.
Injectable collagenase clostridium histolyticum for Dupuytren's contracture.
Dupuytren's contracture: fibroblast contraction? An ultrastructural study.
Does medication overuse headache represent a behavior of dependence?
Chronic migraine plus medication overuse headache: two entities or not?
Advice alone vs. structured detoxification programmes for medication overuse headache: a prospective, randomized, open-label trial in transformed migraine patients with low medical needs.